Pulmonary Function and Flow-Volume Loop Patterns in Patients With Tracheobronchomalacia: Is There an Independent Effect?

Eberlein, Michael; Bölükbas, Servet; Reed, Robert M.

doi:10.4187/respcare.02529

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…Flow-limiting segments are like waterfalls because they separate the airway into upstream and downstream segments, and changes in pressure in the downstream segment do not affect flow from the upstream segment 2,3 . Consistent with our observation 2 , tracheobronchomalacia was not found to be the flow-limiting segment and there was no correlation between the FEV 1 and central airway collapse 4,5 .…”

Section: To the Editorsupporting

confidence: 90%

Excessive dynamic airway collapse and lung transplantation

Eberlein

2016

The Journal of Heart and Lung Transplantation

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Section: To the Editorsupporting

confidence: 90%

Excessive dynamic airway collapse and lung transplantation

Eberlein

2016

The Journal of Heart and Lung Transplantation

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“…6,13 Helpful clues during these tests include reduced maximum forced expiratory flow, a biphasic expiratory curve, flow oscillations, and notching, but these are not universally present. 10,18,[20][21][22] Examples of these abnormalities are presented in the flow-volume loops in Figure 3.…”

Section: Diagnosismentioning

confidence: 99%

Central Airway Collapse, an Underappreciated Cause of Respiratory Morbidity

Abia‐Trujillo

Majid

Johnson

et al. 2020

Mayo Clinic Proceedings

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Dyspnea, cough, sputum production, and recurrent respiratory infections are frequently encountered clinical concerns leading patients to seek medical care. It is not unusual for a well-defined etiology to remain elusive or for the therapeutics of a presumed etiology to be incompletely effective. Either scenario should prompt consideration of central airway pathology as a contributor to clinical manifestations. Over the past decade, recognition of dynamic central airway collapse during respiration associated with multiple respiratory symptoms has become more commonly appreciated. Expiratory central airway collapse may represent the answer to this diagnostic void. Expiratory central airway collapse is an underdiagnosed disorder that can coexist with and mimic asthma, chronic obstructive pulmonary disease, and bronchiectasis. Awareness of expiratory central airway collapse and its spectrum of symptoms is paramount to its recognition. This review includes clear definitions, diagnostics, and therapeutics for this challenging condition. We performed a narrative review through the PubMed (MEDLINE) database using the following MeSH terms: airway collapse, tracheobronchomalacia, tracheomalacia, and bronchomalacia. We include reports from systematic reviews, narrative reviews, clinical trials, and observational studies from 2005 to 2020. Two reviewers evaluated potential references. No systematic reviews were found. A total of 28 references were included into our review. Included studies report experience in the diagnosis and/or treatment of dynamic central airway collapse; case reports and non-English or non-Spanish studies were excluded. We describe the current diagnostic dilemma, highlighting the role of dynamic bronchoscopy and tracheobronchial stent trial; outline the complex therapeutic options (eg, tracheobronchoplasty); and present future directions and challenges.

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Pulmonary Function and Flow-Volume Loop Patterns in Patients With Tracheobronchomalacia: Is There an Independent Effect?

Cited by 2 publications

References 9 publications

Excessive dynamic airway collapse and lung transplantation

Excessive dynamic airway collapse and lung transplantation

Central Airway Collapse, an Underappreciated Cause of Respiratory Morbidity

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