Pulmonary hypertension in systemic lupus erythematosus.

Abstract

Controlled trial of medical treatment of active chronic otitis media Active chronic otitis media is a common condition affecting 0 6%,' of adults in the United Kingdom. Initial management is usually by general practitioners, who annually prescribe systemic and topical antibiotics on at least 178 000 and 73 000 occasions respectively (unpublished observations). Despite this there have been few studies of the efficacy of antibiotics,'-4 and no study has included a control group of untreated patients or of patients treated solely by aural toilet. We undertook a controlled study comparing appropriate systemic or topical antibiotic treatment with weekly aural toilet and insufflation of boric acid and iodine powder.

Pulmonary Hypertension in Systemic Lupus Erythematosus: A Report of an Autopsied Case.

“…Pulmonary hypertension (PH) is a rare complication in SLE; only a few reports of such a complication have been published until recently (1)(2)(3)(4)(5)(6)(7)(8)(9). Wepresent here an autopsied case of SLEassociated with PH, Raynaud's phenomenonand a lupus anticoagulant.…”

“…PH is also found in rare occasions in rheumatoid arthritis, dermatomyositis or primary Sjogren's syndrome. The first report of isolated SLEcases with demonstrable PH appeared in 1962 (13), and only recently several articles have been published (1)(2)(3)(4)(5)(6)(7)(8)(9). Recent studies using Doppler echocardiography and right heart catheterization indicate that the incidence of PH is 14%in SLE (14).…”

Imaging Findings in Systemic Lupus Erythematosus

“…Pulmonary arterial hypertension occurs in 14% of SLE patients secondary to chronic interstitial disease and in 25% of SLE patients with aPL-ab syndrome (20). The increased prevalence in aPL-ab syndrome is thought to be due to recurrent pulmonary emboli (20).…”

“…Pulmonary arterial hypertension is an increasingly recognized complication of SLE and is more common in patients with aPL-ab syndrome (19,20). Pulmonary arterial hypertension occurs in 14% of SLE patients secondary to chronic interstitial disease and in 25% of SLE patients with aPL-ab syndrome (20).…”

Pulmonary Hypertension and the Antiphospholipid Syndrome

“…The association of antiphospholipid antibodies and PH is beginning to draw attention of many rheumatologists. This association in SLE patients was originally described by Asherson et al (2). In their series of 6 SLEpatients with PH, 5 were positive for lupus anticoagulant activity.…”