Pulmonary Ventilatory Function in Talcosis of Lung

Current intelligence bulletin 62: asbestos fibers and other elongate mineral particles: state of the science and roadmap for research.

“…Workers exposed to talc † † have long been recognized to have an increased risk of developing pulmonary fibrosis, often referred to as talc pneumoconiosis [Siegel et al 1943;Kleinfeld et al 1955]. Talc-exposed workers have also been reported to have an increased prevalence of pleural abnormalities, including pleural thickening and pleural plaques [Siegel et al 1943;Gamble et al 1982].…”

“…Several more recent epidemiological studies and reviews have been conducted of workers employed in talc mines and mills in upstate New York [Brown et al 1979[Brown et al , 1990Kleinfeld et al 1967Kleinfeld et al , 1974Stille and Tabershaw 1982;Gamble 1993;Honda et al 2002;Gamble and Gibbs 2008]. † †…”

“…That code lacked specificity and sensitivity for mesothelioma; in a study of Massachusetts deaths, many non-mesothelioma malignancies involving the pleura were assigned code 163 and most mesotheliomas were not assigned code 163 [Davis et al 1992]. The more recent ICD-10 system, which has been used since 1999 to code death certificate data in the United An excess of lung cancer has also been reported following several epidemiological studies of New York talc mines and mills [Kleinfeld et al 1967[Kleinfeld et al , 1974Brown et al 1990; Stille and Tabershaw 1982;Honda et al 2002]. The most extensive research has been conducted on workers at the talc mine and mills owned by RT Vanderbilt Company, Inc. (RTV), located in St. Lawrence County.…”

Non-Infectious Granulomatous Lung Disease: Imaging Findings with Pathologic Correlation

“…History of occupational exposure or drug addiction is the major clue to diagnosis [ 87 88 89 90 91 ]. Clinically, patients with pulmonary talcosis can range from asymptomatic to severe disease [ 92 ]. A wide variety of pulmonary complications, including asthma exacerbation, barotrauma, hilar lymphadenopathies, and bullous emphysema, may be associated with the inhalation of talc, silica, and lactose [ 93 ].…”

Occupational exposure to talc containing asbestos: morbidity, mortality, and environmental studies of miners and millers.

“…Previous studies by Kleinfeld et al (5,6) of asbestiform talc miners and millers in this district have demonstrated significantly increased proportional mortality due to both malignant and nonmalignant respiratory diseases. Morbidity studies also have indicated increased symptoms and X-ray and lung function changes consistent with pneumoconiosis (7,8,9,10,11,12). More 1 recently a talc mlnlng company in this district maintained that these studies were not applicable to all talcs in the Gouverneur Talc District.…”