Pulpo-dentin complex response after direct capping with self-etch adhesive systems

Abstract

Abstract:The purpose of the present study was to evaluate morphologically the response of feline teeth pulp to direct pulp capping with two different self-etch adhesive systems. Twenty-four cavities in feline teeth were mechanically exposed and assigned to one of two experimental groups: AdheSE + Tetric Ceram (the ASE group), or Adper Prompt L-Pop + Filtek Supreme (the APLP group). There was also a control group Dycal Ca(OH) 2 liner + Amalgam (the CH group eight teeth), and six teeth were used as an intact control group. The animals were sacrificed after 40 days. The teeth were removed and processed for standard histological evaluation, using a scoring system for inflammatory cell response, pulp tissue disorganisation, reparative tissue formation, and the presence of bacteria. Statistical analysis revealed no significant differences between the ASE and APLP selfetching resin systems during the observation period. The majority of the specimens presented inflammatory pulp response with tissue disorganisation and a lack of dentinal bridge formation. CH capping resulted in a significantly smaller inflammatory pulp response and a considerably higher incidence of reparative dentin formation. ASE and APLP were comparably effective as direct pulp capping materials, but their application resulted in significantly greater pulp tissue damage than CH capping. Further in vivo human studies are necessary to determine which adhesive resin systems should be clinically used for direct pulp capping without incurring severe damage to the pulpal tissue.

Response of exposed human pulp to application of a hemostatic agent and a self-etch adhesive

“…[35] However, it has been suggested that data obtained from animal teeth should not be directly extrapolated to human clinical conditions. [25,36] Thus, in this study, we chose to examine human teeth.…”

Evaluation of biocompatibility of four different one-step self-etching adhesives by animal experimental method

“…Especially after cervical restorations, prolonged contact of Bis-GMA with gingival tissues may cause lichenoid reactions or irritations in the oral mucosa. 29 In a study by Nowicka et al 30 , the response of the pulpdentin complex was analyzed after direct pulp capping treatment using self-etch adhesive systems. In most of the specimens, pulpal reaction and lack of dentin bridge formation occurred with tissue disruption.…”

Strategies to Improve Biocompatibility of Dental Materials

“…Adverse reactions to dental materials occur in patients and dental personnel [1••]. Local reactions take place at the exposure site, e.g., dental pulp and pulp inflammation after pulp capping with adhesives and resin-based composites has been described [2][3][4][5], which was related to substances released from the applied materials. Also, inhibition of biomineralization after pulp capping with adhesives was observed [6] and can also be related to eluted substances from dental materials such as acrylic monomers [7, 8••].…”