Pulsed electromagnetic field treatment failure in radius non-united fracture healing

Madroñero, Ana Belén; Pitillas, I.; Manso, F.J.

doi:10.1016/0141-5425(88)90153-7

Cited by 9 publications

(2 citation statements)

References 3 publications

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“…Sixty‐eight studies were removed after full‐text retrieval for a variety of reasons including study protocol [Hannemann et al, 2011], non‐randomized controlled trials [Wang et al, 2005; Abdelrahim et al, 2011; Assiotis et al, 2012; Yang et al, 2012; Li, 2013; Qian, 2014; Xie et al, 2014], not relevant to fractures [Grote et al, 2007; Elsisi et al, 2015], or not relevant to effect of PEMF [Scott and King, 1994; Linovitz et al, 2002; Kerr‐Valentic et al, 2003; Hannemann et al, 2015]. Moreover, three [Madronero et al, 1988; Gupta et al, 2009; Boyette and Herrera‐Soto, 2012] were excluded because of the lack of a control group. Finally, 22 trials ( n = 1,468 participants) met our eligibility criteria for systematic review and quantitative synthesis.…”

Section: Resultsmentioning

confidence: 99%

Effectiveness of Pulsed Electromagnetic Fields on Bone Healing: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Peng

Xiong

et al. 2020

Bioelectromagnetics

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The effect of pulsed electromagnetic field (PEMF) on bone healing is still uncertain and it has not been established as a standardized treatment. The aim of this systematic review and meta‐analysis is to evaluate the effect of PEMF on bone healing in patients with fracture. We searched CNKI, Wan Fang, VIP, EMbase, PubMed, CENTRAL, Web of Science, Physiotherapy Evidence Database, and Open Grey websites for randomized controlled trials (published before July 2019 in English or Chinese) comparing any form of PEMF to sham. Reference lists were also searched. Related data were extracted by two investigators independently. The bias risk of the articles and the evidence strength of the outcomes were evaluated. Twenty‐two studies were eligible and included in our analysis (n = 1,468 participants). The pooled results of 14 studies (n = 1,131 participants) demonstrated that healing rate in PEMF group was 79.7% (443/556), and that in the control group was 64.3% (370/575). PEMF increased healing rate (RR = 1.22; 95% confidence interval [CI] = 1.10–1.35; I2 = 48%) by the Mantel–Haenszel analysis, relieved pain (standardized mean difference (SMD) = −0.49; 95% CI = −0.88 to −0.10; I2 = 60%) by the inverse variance analysis, and accelerated healing time (SMD = −1.01; 95% CI = −2.01 to −0.00; I2 = 90%) by the inverse variance analysis. Moderate quality evidence suggested that PEMF increased healing rate and relieved pain of fracture, and very low‐quality evidence showed that PEMF accelerated healing time. Larger and higher quality randomized controlled trials and pre‐clinical studies of optimal frequency, amplitude, and duration parameters are needed. © 2020 Bioelectromagnetics Society.

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Section: Resultsmentioning

confidence: 99%

Effectiveness of Pulsed Electromagnetic Fields on Bone Healing: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Peng

Xiong

et al. 2020

Bioelectromagnetics

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“…Among these applications are: excitation of neural tissues by means of time-varying magnetic field [14], hyperthermia therapy of cancer by a magnetic induction heating [15], utilization of magnetic pellets implanted in the head to deliver drugs and therapies directly into deep brain tissues [16], retention of dental prosthetic appliances by permanent implanted magnets [17], recovery of sick injured cells and fractured bones by generated magnetic fields around the area to be treated [18], detection of inflammations and necroses [19] and treatment of delayed union bone fractures and back pain [20] by magnetic fields and magnetic resonance imaging, which is one of the breakthroughs in medical diagnosis this century.…”

Section: Introductionmentioning

confidence: 99%