Purification, structural elucidation, and anti-inflammatory effect of a water-soluble 1,6-branched 1,3-α-d-galactan from cultured mycelia of Poria cocos

Purification and characterization of a glucan from Bacillus Calmette Guerin and the antitumor activity of its sulfated derivative

“…Nevertheless, less investigation was carried out on the structural elucidation of BCG-PSA. What's more, structure characteristic is necessary for understanding the mechanism of biological activity and expounding the structure-activity relationships (Lu, Cheng, Lin, & Chang, 2010). Thus, it is significant to clarify the structure of the BCG-PSA.…”

Preparation, chain conformation and anti-tumor activities of water-soluble phosphated (1→3)-α-d-glucan from Poria cocos mycelia

“…Poria cocos is one of the most significant Chinese herbs, and polysaccharides from this fungus have attracted considerably attention in the fields of biochemistry and pharmacology because of their biological activities (Chen, Tang, Chen, Wang, & Li, 2010;Chihara, Hamuro, Maeda, Arai, & Fukuoka, 1970;Kanayama, Adachi, & Togami, 1983;Ke, Lin, Chen, Ji, & Shu, 2010;Lee et al, 2004;Lu, Cheng, Lin, & Chang, 2010;Wang, Yu, & Mao, 2009). In our previous work, water-soluble and water-insoluble polysaccharides were isolated from P. cocos mycelia produced in a pilot-scale fermenter.…”

Preliminary Characterization of a Homogeneous Polysaccharide with Anticomplement Activity from Sijunzi Decoction

“…The Atractylodis macrocephalae Koidz polysaccharides are found to be composed of Rha, Ara, Xyl, Man, Glc, and Gal, with a backbone constructed by Glc and the branches constituted by Rha [34]. It has also been reported that polysaccharides extracted from P. cocos and fractionated with size-exclusion column chromatography gave a water-soluble 1,6-branched 1,3-alpha-D-Gal structure [35]. Polysaccharides from Liquorice roots have been found to contain about 81% carbohydrates and 19% protein, with the polysaccharide content to mainly contain Ara, Gal, Glc, and GlcA [9].…”