Purpura Hyperglobulinemica Terminating in Multiple Myeloma

Rogers, Wayne R.

doi:10.1001/archinte.1957.00260090134019

Cited by 14 publications

(8 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…5 Rogers and Welch described a male patient who had hypergammaglobulinemic purpura a decade prior to his diagnosis of myeloma. 4 Shalit et al reported a case of a male patient who was admitted for recurrent purpura. Skin biopsy showed IgA deposition in blood vessels.…”

Section: Discussionmentioning

confidence: 99%

Hypergammaglobulinemic purpura of Waldenström—Unusual and impressive case in a patient with myeloma: A case report

DeBiasio

Cyr

Petkiewicz

et al. 2022

SAGE Open Medical Case Reports

View full text Add to dashboard Cite

Background: Hypergammaglobulinemic purpura of Waldenström is an uncommon disease, which presents mostly in women on the lower extremities. It is sometimes associated with underlying immune dysregulation. Sjögren syndrome is the most common association; however, rare occurrences of the self-resolving syndrome with lymphoma or myeloma have been reported. Case Summary: We describe an unusual and impressive presentation of hypergammaglobulinemic purpura of Waldenström in an elderly female patient with myeloma. Notably, the patient did not have any concurrent connective tissue diseases. Despite her florid presentation, her hypergammaglobulinemic purpura of Waldenström spontaneously resolved within a few days. Conclusion: Hypergammaglobulinemic purpura of Waldenström is a self-resolving but recurrent syndrome, which may be associated with autoimmune disorders or rarely myeloma. Early diagnosis of the syndrome may avoid unnecessary treatment interventions and should prompt screening for underlying diseases.

show abstract

Section: Discussionmentioning

confidence: 99%

Hypergammaglobulinemic purpura of Waldenström—Unusual and impressive case in a patient with myeloma: A case report

DeBiasio

Cyr

Petkiewicz

et al. 2022

SAGE Open Medical Case Reports

View full text Add to dashboard Cite

show abstract

“…In one of these, the paraprotein was not identified, while in the other it was IgG type kappa. 2 additional patients had the classical symptoms of HGP without paraproteinemia, preceding the de velopment of MM [8,9].…”

Section: Discussionmentioning

confidence: 99%

Hyperglobulinemic Purpura in the Course of Multiple Myeloma

Shalit¹,

Bar-Sela²,

Leviatan³

et al. 1980

Acta Haematol

View full text Add to dashboard Cite

show abstract

“…The course of BHGP is benign especially in the primary type, and treatment is not required. However, the patient should be followed throughout his life because of the possibility of developing other disease such as Sjogren syndrome, lupus erythematosus and in rare casesmultiple myeloma (10,11).…”

Section: Case Reportmentioning

confidence: 99%

Hypergammaglobulinemic Purpura and Cryoglobulinemia

Sonnenblick

Gelmont

Jacobsohn

et al. 1978

The Journal of Dermatology

View full text Add to dashboard Cite

Primary hypergammaglobulinemic purpura in an 84 year old woman is described. In addition to her advanced age, she also showed cryoglobulinemia. The patient was further studied by immunofluorescent staining of the skin biopsy specimen, which showed deposition of IgG, IgM, fibrinogen and β1C in the vessel walls. These findings would seem to indicate involvement of the complement system in the pathogenesis of the vasculitis in this entity.

show abstract

Purpura Hyperglobulinemica Terminating in Multiple Myeloma

Cited by 14 publications

References 10 publications

Hypergammaglobulinemic purpura of Waldenström—Unusual and impressive case in a patient with myeloma: A case report

Hypergammaglobulinemic purpura of Waldenström—Unusual and impressive case in a patient with myeloma: A case report

Hyperglobulinemic Purpura in the Course of Multiple Myeloma

Hypergammaglobulinemic Purpura and Cryoglobulinemia

Contact Info

Product

Resources

About