Pushing Retinal Imaging Forward: Innovations and Their Clinical Meaning – The 2022 Ophthalmologica Lecture

Abstract

Retinal imaging has greatly expanded our understanding of various pathological conditions. This article presents a summary of the key points covered during the 2022 Ophthalmologica Lecture held at the Euretina Congress in Hamburg. The first part of the article focuses on the use of optical coherence tomography angiography to examine and comprehend the choroid in age-related macular degeneration (AMD). Subsequently, we delve into the discussion of the “postreceptor neuronal loss” theory in AMD, which was studied using en face structural optical coherence tomography (OCT). Following that, we explore pertinent findings obtained through cross-sectional OCT in retinal and optic nerve diseases, such as AMD, diabetic macular edema, pathologic myopia, central serous chorioretinopathy, and Leber’s hereditary optic neuropathy.

Deep Learning in Neovascular Age-Related Macular Degeneration

“…Consequently, AMD presents itself as a complex array of disorders with a multifactorial etiology [ 2 ]. Regardless of the etiology, AMD is ultimately considered as a disease characterized by the dysfunction of the unit comprised of photoreceptors, retinal pigment epithelium (RPE), Bruch’s membrane and choriocapillaris [ 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ].…”