Liver 2018
DOI: 10.1136/gutjnl-2018-bsgabstracts.228
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PWE-086 Improving identification and management of alcohol-related brain injury (ARBI) in acute care settings

Abstract: All patients presented with acute elevations in transaminases , ). Immungolulins and autoantibodies were normal. One patient developed acute synthetic dysfunction with no encephalopathy (Bilirubin 64, INR 1.5). 79% received steriods (mean dose:1.3 mg/kg); 34% MMF. Steroid refractory ALI was treated with anti-thymocyte globulin (ATG) in 4 patients.Pathological findings (n=6 liver biopsies) revealed lobular hepatitis and myelo-lymphoid cell infiltrate/aggregates (CD3+, CD8+,CD68+). Patients with severe, refracto… Show more

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“…Detection and diagnosis of ARCI at the earliest opportunity is crucial to facilitating appropriate referral and treatment [ 6 , 19 ]. The major features of presentation in this patient group relate to cognitive impairments that affect memory and executive functioning with subsequent behavioural change, features known to adversely affect outcomes [ 20 ].…”
Section: Introductionmentioning
confidence: 99%
“…Detection and diagnosis of ARCI at the earliest opportunity is crucial to facilitating appropriate referral and treatment [ 6 , 19 ]. The major features of presentation in this patient group relate to cognitive impairments that affect memory and executive functioning with subsequent behavioural change, features known to adversely affect outcomes [ 20 ].…”
Section: Introductionmentioning
confidence: 99%