Pyridoxinium picrate

Abstract

The title compound [systematic name: 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridinium 2,4,6-trinitrophenolate], C(8)H(12)NO(3)(+)xC(6)H(2)N(3)O(7)(-), is a complex of picric acid with pyridoxine. The asymmetric part of the unit cell contains one pyridoxinium cation and one picrate anion. The aromatic rings of the picrate anion and the pyridoxinium cation are inclined with a dihedral angle of 83.19 (7) degrees . An intramolecular hydrogen bond between OH and a nearby CH(2)OH group is observed in the cation. The hydrophobic layers at y = {1/2} are packed between the hydrophilic layers at y = 0.

Spectroscopic, thermal, biological activity, molecular docking and density functional theoretical investigation of novel bis Schiff base complexes

“…at room temperature (which is in the normal range μ eff = 2.9-3.7 B.M.) and three bands at ν 2 : (15,015) cm −1 : 3…”

“…The effects of Schiff bases and functional groups structure in the coordination sphere have been studied. [1][2][3][4][5][6][7][8][9][10][11] The azomethine group (-C=N-) of Schiff bases and their metal complexes have been of interest for long periods of time due to their unusual structural properties [12] and multiple applications in various biological activities. [13] Some complexes are known to be effective against rheumatoid arthritis, anti-ulcer activity as Cu(II) [14] because acidic anti-inflammatory agents of copper in generally preventing gastrointestinal damage.…”

Synthesis, spectroscopic characterization, biological screening and in vitro cytotoxic studies of 4‐methyl‐3‐thiosemicarbazone derived Schiff bases and their Co (II), Ni (II), Cu (II) and Zn (II) complexes

“…The analytical data suggested the formation of different colored solid complexes, stable at room temperature and non-electrolytic in nature as the molar conductance values of the complexes were found to be in between 11-20 ohm −1 cm 2 mol −1. [34,35] All the compounds were soluble in MeOH, EtOH, CDCl 3 , DMF and DMSO but were insoluble in water. The ligands were chelated to all metal ions via nitrogen atom of azomethine group and sulphur atom of thionyl group in thione form without the replacement of hydrogen atom.…”

Cocrystallization of Nutraceuticals

“…The structure of pyridoxinium picrate (CELMUC) 142. Biotin reveals the presence of a stable R 2 2 (8) acid-amide dimer as the hydrogen-bonded interaction for both carboxylic acids groups (BIOTIN01).…”