Pyrimidine-2-carboxamide

Abstract

In the crystal strucuture of the title compound, C5H5N3O, which was obtained upon recrystallization of 2-cyano­pyrimidine from aqueous sodium hydroxide, the amide group is twisted with respect to the aromatic ring by 24.9 (1)°. π–π stacking is observed between partially overlapped rings at a face-to-face separation of 3.439 (6) Å. The structure features a centrosymmetric pair of inter­molecular N—H⋯O hydrogen bonds. Another N—H⋯O hydrogen bond between adjacent mol­ecules links them into a helical chain motif.

Diaquabis(pyrimidine-2-carboxylic acid-κ2N,O)cobalt(II) dichloride

“…π-π stacking is not observed in this crystal structure, which is different from the situation in a related Cu II complex with pyrimidine-2-carboxylate (Zhang et al, 2008). It may be due to extensive hydrogen bonding network involving coordinated water molecules and counter Clanions.…”

“…For general background, see: Cheng et al (2000); Wu et al (2003). For related structures, see: Rodriquez-Dieguez et al (2007); Zhang et al (2008).…”