Pyrrolidine modified PANF catalyst for asymmetric Michael addition of ketones to nitrostyrenes in aqueous phase

Abstract

Three chiral pyrrolidine functionalized polyacrylonitrile fiber catalysts have been designed, prepared, and evaluated for their catalytic performance in asymmetric Michael addition of ketones to nitrostyrenes in water.

A comprehensive review of flow chemistry techniques tailored to the flavours and fragrances industries

“…Wang and Zhang et al applied PNAF-supported catalyst in flow for asymmetric conjugate addition of cyclohexanone ( 65 ) and trans- β - nitrostyrenes (e.g., 74 ) [ 205 ]. The PNAF enables the use of greener solvents such as water and ethanol in the Michael reaction and creates a stable and robust heterogeneous catalyst which can be used over 4 cycles with comparable results ( Scheme 44 ).…”

Phosphorylated Polyacrylonitrile Fibers as an Efficient and Greener Acetalization Catalyst

“…The fact that strong polar solvents favor the acetalization could be ascribed to the specificm icro-environment of the fiber catalyst and both surface synergies and interfacea cceleration have an important effect on the catalytic activity of the heterogeneous catalyst. [33] Our previous work showedt hat the functionalized PANF catalyst is ak ind of multilayer modification that can be constructed into as pecific three-dimensional environment [34] like some interlayerr egions of layered solids such as layered double hydroxides [35] ,w hich shows higher catalytic activities than those monolayer materials. Because of the presence of many hydrophilicg roups (OH, CN, etc.…”

Biocatalytic asymmetric Michael addition reaction ofl-arginine to fumarate for the green synthesis of N-(([(4S)-4-amino-4-carboxy-butyl]amino)iminomethyl)-l-aspartic acid lithium salt (l-argininosuccinic acid lithium salt)

“…18 Green chemistry approaches have focussed on developing hydrolases for Michael-type additions in organic solvents 19 and on replacing organic solvents, e.g. by green solvents 20 and ionic liquids, 21 solvent-free reactions in ball mills 22 and reactions on water. 23 As catalytic asymmetric Michael addition reactions in water represent an ideal green synthetic methodology for creating molecular complexity from simple building blocks by the formation of new carbon-carbon bonds, the corresponding highly selective and suitable catalysts need to be developed.…”