QT interval dynamics and triggers for QT prolongation immediately following cardiac arrest

Cohen, Roi Bar; Dai, Matthew; Aizer, Anthony; Barbhaiya, Chirag R.; Peterson, Connor; Bernstein, Scott; Park, David; Spinelli, Michael; Chinitz, Larry A.; Jankelson, Lior

doi:10.1016/j.resuscitation.2021.02.029

Cited by 6 publications

(1 citation statement)

References 13 publications

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“…Of note, the corrected QT (QTc)/corrected JT (JTc) interval can be significantly prolonged after resuscitation or in the setting of hypothermia, independently from QT-prolonging drugs, and normalization should be only expected beyond Day 6 after the acute event. 132 , 133 Any potentially offending drug must be withdrawn, and drugs known to prolong the QT interval, except AADs used to treat the ES, must be avoided. Early correction of serum electrolyte levels (K + , Mg 2+ , and Ca 2+ ) is indicated 134–136 ; in cases of TdP, i.v.…”

Section: Acute Managementmentioning

confidence: 99%

Management of patients with an electrical storm or clustered ventricular arrhythmias: a clinical consensus statement of the European Heart Rhythm Association of the ESC—endorsed by the Asia-Pacific Heart Rhythm Society, Heart Rhythm Society, and Latin-American Heart Rhythm Society

Lenarczyk,

Zeppenfeld,

Tfelt-Hansen

et al. 2024

Europace

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Electrical storm (ES) is a state of electrical instability, manifesting as recurrent ventricular arrhythmias (VAs) over a short period of time (three or more episodes of sustained VA within 24 h, separated by at least 5 min, requiring termination by an intervention). The clinical presentation can vary, but ES is usually a cardiac emergency. Electrical storm mainly affects patients with structural or primary electrical heart disease, often with an implantable cardioverter-defibrillator (ICD). Management of ES requires a multi-faceted approach and the involvement of multi-disciplinary teams, but despite advanced treatment and often invasive procedures, it is associated with high morbidity and mortality. With an ageing population, longer survival of heart failure patients, and an increasing number of patients with ICD, the incidence of ES is expected to increase. This European Heart Rhythm Association clinical consensus statement focuses on pathophysiology, clinical presentation, diagnostic evaluation, and acute and long-term management of patients presenting with ES or clustered VA.

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Section: Acute Managementmentioning

confidence: 99%

Management of patients with an electrical storm or clustered ventricular arrhythmias: a clinical consensus statement of the European Heart Rhythm Association of the ESC—endorsed by the Asia-Pacific Heart Rhythm Society, Heart Rhythm Society, and Latin-American Heart Rhythm Society

Lenarczyk,

Zeppenfeld,

Tfelt-Hansen

et al. 2024

Europace

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Importance of exercise stress testing in evaluation of unexplained cardiac arrest survivor

et al. 2023

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Background In sudden cardiac arrest survivors without an immediately identifiable cause, additional extensive yet individualised testing is required. Methods We describe 3 survivors of sudden cardiac arrest in whom exercise stress testing was not performed during the initial hospital admission. Results All 3 patients were incorrectly diagnosed with long QT syndrome based on temporary sudden cardiac arrest–related heart rate–corrected QT interval prolongation, and exercise stress testing was not performed during the initial work-up. When they were subjected to exercise stress testing during follow-up, a delayed diagnosis of catecholaminergic polymorphic ventricular tachycardia (CPVT) was made. As a result, these patients were initially managed inappropriately, and their family members were initially not screened for CPVT. Conclusion In sudden cardiac arrest survivors without an immediately identifiable cause, omission of exercise stress testing or erroneous interpretation of the results can lead to a delayed or missed diagnosis of CPVT, which may have considerable implications for survivors and their family.

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Clinical Management of Inherited Arrhythmias

Moore,

Laksman,

Roston

et al. 2024

Reference Module in Biomedical Sciences

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QT interval dynamics and triggers for QT prolongation immediately following cardiac arrest

Cited by 6 publications

References 13 publications

Management of patients with an electrical storm or clustered ventricular arrhythmias: a clinical consensus statement of the European Heart Rhythm Association of the ESC—endorsed by the Asia-Pacific Heart Rhythm Society, Heart Rhythm Society, and Latin-American Heart Rhythm Society

Management of patients with an electrical storm or clustered ventricular arrhythmias: a clinical consensus statement of the European Heart Rhythm Association of the ESC—endorsed by the Asia-Pacific Heart Rhythm Society, Heart Rhythm Society, and Latin-American Heart Rhythm Society

Importance of exercise stress testing in evaluation of unexplained cardiac arrest survivor

Clinical Management of Inherited Arrhythmias

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