Quadricuspid aortic valve: A rare etiology of aortic regurgitation

Abstract

Quadricuspid aortic valve is a rare cause of aortic insufficiency. We report two unusual cases of this valvular pathology associated with a dilatation of the aortic root. The mechanism leading to this valve incompetence is incompletely understood and is discussed in regard to these cases.

Quadricuspid Aortic Valve and Anomalous Systemic Venous Connection in a Patient With Cat-Eye Syndrome

“…[3][4][5][6] It can appear as an isolated congenital anomaly but may also be associated with other cardiac malformations. Furthermore, it should be realized that it is part of a continuum of dysmorphic aortic valves.…”

“…4 In quadricuspid aortic valves, the most common complications include regurgitation and coronary artery anomalies. [3][4][5][6] The mechanism causing valvular incompetence is incompletely understood. The functional aspect of the quadricuspid valve is represented mainly by pure insufficiency.…”

“…Whether this is the case in our patient with a quadricuspid valve cannot be confirmed. [3][4][5][6] The natural history of a quadricuspid aortic valve is progression to valve regurgitation in varying severity, which is rare before adulthood and mainly occurs later in life. [3][4][5][6] The diagnosis is commonly made between the fifth and sixth decades and is more frequently in male patients.…”

“…[3][4][5][6] The natural history of a quadricuspid aortic valve is progression to valve regurgitation in varying severity, which is rare before adulthood and mainly occurs later in life. [3][4][5][6] The diagnosis is commonly made between the fifth and sixth decades and is more frequently in male patients. [3][4][5][6] Diagnosis of quadricuspid aortic valve is usually made noninvasively by transthoracic echocardiography.…”

“…[3][4][5][6] The diagnosis is commonly made between the fifth and sixth decades and is more frequently in male patients. [3][4][5][6] Diagnosis of quadricuspid aortic valve is usually made noninvasively by transthoracic echocardiography. In our case, the quadricuspid aortic valve showed mild ascending aortic dilation but no coronary anomalies.…”