“…Entrepreneurship is a prominent topic of research across several fields (Acs and Audretsch, 2006[108]), many of which fall under the umbrella of regional science. A great interest in entrepreneurship arguably comes from understanding that start-ups, particularly small and innovative ones, play a central role in economic performance of regions (Acs, 2006[109]; Audretsch and Keilbach, 2004 [110]; Birch, 1987[111]; Malecki, 1993[112]). It comes as no surprise that a vast literature tries to explain entrepreneurial activity within a subnational perspective (Acs et al, 2009[113]; Lee, Florida and Acs, 2004 [114]; Mueller, 2006[115]; Qian, Acs and Stough, 2013 [116]).…”