Quality evaluation methods of chinese medicine based on scientific supervision: recent research progress and prospects

Abstract

Traditional Chinese medicine (TCM) is increasingly getting attention worldwide, as it has played a very satisfactory role in treating COVID-19 during these past 3 years, and the Chinese government highly supports the development of TCM. The therapeutical theory and efficacies of Chinese medicine (CM) involve the safety, effectiveness and quality evaluation of CM, which requires a standard sound system. Constructing a scientific and reasonable CM quality and safety evaluation system, and establishing high-quality standards are the key cores to promote the high-quality development of CM. Through the traditional quality control methods of CM, the progress of the Q-marker research and development system proposed in recent years, this paper integrated the research ideas and methods of CM quality control and identified effective quality parameters. In addition, we also applied these effective quality parameters to create a new and supervision model for the quality control of CM. In conclusion, this review summarizes the methods and standards of quality control research used in recent years, and provides references to the quality control of CM and how researchers conduct quality control experiments.

N1F(Improved-Nephropathy 1 Formula) ameliorates renal interstitial fibrosis via inhibiting extracellular matrix deposition and regulating the FGF23/P38MAPK/Wnt pathway

“…Chinese medicine has a long history of treating various diseases with few toxic side effects [21]. Chinese herbal formulas usually consist of a variety of herbs with synergistic effects for the treatment of various diseases [22] [23]. Studies have confirmed that Chinese herbs have robust pharmacological effects and have received more and more attention in the treatment of CKD [24][25] [26].…”