Quality of Life Before and After Major Lung Resection for Lung Cancer: A Prospective Follow-Up Analysis

Brunelli, Alessandro; Socci, Laura; Refai, Majed; Salati, Michele; Xiumé, Francesco; Sabbatini, Armando

doi:10.1016/j.athoracsur.2007.04.019

Cited by 144 publications

(113 citation statements)

References 16 publications

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“…(23,27) One study demonstrated that, within one month of the surgery, lower values are obtained for most scales, and that these values return to preoperative levels from the third month onward. (28) The authors of that study also reported that cancer patients presented a worse initial QoL than did the general population, and that, except for general health, the scores on all scales remained below 50% in cancer patients even after the third postoperative month, which is in accordance with our results. In addition, those authors found that physical functioning, social functioning and mental health did not change over time.…”

Section: Discussionsupporting

confidence: 82%

Avaliação da função pulmonar e da qualidade de vida em pacientes submetidos à ressecção pulmonar por neoplasia

et al. 2009

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Objective: To evaluate the effects that pulmonary resection has on pulmonary function and quality of life (QoL) in patients with primary or metastatic lung cancer. Methods: This was a prospective cohort study involving all patients submitted to pulmonary resection for cancer between September of 2006 and March of 2007 at the A. C. Camargo Hospital in São Paulo, Brazil. Patients underwent spirometry in the preoperative period and at six months after the surgical procedure. After a postoperative period of six months, the patients completed an overall QoL questionnaire (the Medical Outcomes Study 36-item Short-form Health Survey) and another one, specific for respiratory symptoms (the Saint George's Respiratory Questionnaire). The scores obtained in our study were compared with those previously obtained for a general population and for a population of patients with COPD. Results: We included 33 patients (14 males and 19 females), ranging in age from 39 to 79 years. All of the patients, smokers and nonsmokers alike, presented significant worsening of pulmonary function. The mean scores on the overall QoL questionnaire were approximately 5% lower than those obtained for the general population. The scores of various domains of the symptom-specific QoL questionnaire were 50-60% lower than those obtained for the general population and approximately 20% higher than those obtained for the population with COPD. Conclusions: Pulmonary resection has a direct negative impact on pulmonary function and QoL, especially on the QoL related to aspects directly linked to pulmonary function. We highlight the importance of preoperative assessment of pulmonary function in patients undergoing pulmonary resection, in order to predict their postoperative evolution.Keywords: Thoracic surgery; Lung neoplasms/surgery; Spirometry; Quality of life; Questionnaires. ResumoObjetivo: Avaliar as repercussões da ressecção pulmonar sobre a função pulmonar e a qualidade de vida (QV) de pacientes com câncer de pulmão primário ou metastático. Métodos: Estudo de coorte prospectivo que incluiu todos os pacientes que realizaram ressecção pulmonar por neoplasia no Hospital A. C. Camargo entre setembro de 2006 e março de 2007. Os pacientes foram avaliados no pré-operatório e após seis meses do procedimento cirúr-gico através de espirometria. Após seis meses de pós-operatório, os pacientes responderam a um questionário de QV geral (Medical Outcomes Study 36-item Short-form Health Survey) e um específico para sintomas respiratórios (Saint George's Respiratory Questionnaire). Os valores de QV obtidos foram comparados a valores de uma população geral e aos de uma população de portadores de DPOC. Resultados: Foram incluídos 33 pacientes (14 homens e 19 mulheres), com idade entre 39 e 79 anos. Todos os pacientes, tabagistas ou não, apresentaram piora significativa da função pulmonar. Observamos uma redução de aproximadamente 5% na média dos escores do questionário de QV geral em comparação àquela da população geral. Houve uma redução de 50-60% nos vários d...

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Section: Discussionsupporting

confidence: 82%

Avaliação da função pulmonar e da qualidade de vida em pacientes submetidos à ressecção pulmonar por neoplasia

et al. 2009

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“…This finding was confirmed by other authors who found an additional risk of right sided pneumonectomy in early stage lung cancer with a 5-year survival after right pneumonectomy of only 33% (75). Pneumonectomy is also a consistent factor associated with a poorer quality of life after surgery (76)(77)(78) and greater functional loss (32). The average FEV 1 and DLCO losses three months after pneumonectomy have been reported to be 34% and 20% respectively compared to the preoperative values.…”

Section: Pneumonectomysupporting

confidence: 77%

Preoperative functional workup for patients with advanced lung cancer

Brunelli

2016

J. Thorac. Dis.

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Locally advanced lung cancer remains a surgical indication in selected patients. This condition often demands larger resections. As a consequence preoperative functional workup is of paramount importance to stratify the risk and choose the most appropriate treatment. We reviewed the current evidence on functional evaluation with a special focus on specific aspects related to locally advanced lung cancer stages (i.e., risk after neoadjuvant treatment, pneumonectomy). Evidence is discussed to provide information that could assist clinicians in their preoperative workup of these challenging patients.

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“…Outro estudo também verificou deterioração da QV no primeiro mês após a cirurgia, mas com retorno ao nível pré-operatório no terceiro mês 25,26 . Por outro lado, na presente amostra, a CF apresentou queda até o quarto mês.…”

Section: Discussionunclassified

“…Outro estudo identificou que VEF 1 < 70% do previsto, o número de comorbidades e o número total de sintomas respiratórios, sendo a dispneia o principal, eram alguns preditores de redução da funcionalidade física, assim como na limitação física, saúde geral e função social 30 . Ao contrário de outro estudo, em que foi baixa a correlação VEF 1 e QV, sugere-se não substituir os instrumentos de avaliação específicos 26 . Nosso estudo tem algumas limitações.…”

Section: Discussionunclassified

Avaliação da qualidade de vida e função pulmonar em pacientes com câncer de pulmão

Müller

Silva

Xavier³

2014

cbr

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Quality of Life Before and After Major Lung Resection for Lung Cancer: A Prospective Follow-Up Analysis

Cited by 144 publications

References 16 publications

Avaliação da função pulmonar e da qualidade de vida em pacientes submetidos à ressecção pulmonar por neoplasia

Avaliação da função pulmonar e da qualidade de vida em pacientes submetidos à ressecção pulmonar por neoplasia

Preoperative functional workup for patients with advanced lung cancer

Avaliação da qualidade de vida e função pulmonar em pacientes com câncer de pulmão

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