Quality of Life in Children with Epilepsy in Wah Cantt, Pakistan: A Cross-sectional Study

Haider, Shahzad; Mahmood, Tahir; Hussain, Sajjad; Nazir, Sajid; Shafiq, Sidra; Hassan, Alina

doi:10.37939/jrmc.v24i2.1232

Cited by 4 publications

(6 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…reported this finding in the 12-15-year age group [ 21 ]. Moreover, Shetty et al [ 22 ] and Ohaeri et al [ 23 ] showed more significant associations when older age groups had lower scores of physical pain, emotional health, and memory and language QoL; however, they observed this finding in an adult population unlike our pediatric participants, which may support the hypothesis that being burdened by the disease and its stigma for a longer period and exhaustion of caretakers leads to a decline in several domains in QoL.…”

Section: Discussioncontrasting

confidence: 46%

Quality of Life in Pediatrics With Intractable Epilepsy at King Abdulaziz Medical City, Jeddah, Saudi Arabia: A Cross-Sectional Study

Marghalani¹,

Aljabri²,

Kaneetah³

et al. 2023

Cureus

View full text Add to dashboard Cite

Objective The aim of this study was to assess the cognitive, emotional, social, and physical domains of quality of life (QoL) in pediatric patients with intractable epilepsy with an emphasis on depressed mood and suicidal ideation (SI). Methods This is a cross-sectional study conducted in pediatric neurology outpatient clinics in King Abdulaziz Medical City, Jeddah, Saudi Arabia. The sample consisted of 59 parents whose children aged 4‐14 years of either sex had intractable epilepsy. The Quality of Life in Childhood Epilepsy Questionnaire - 55 (QOLCE‐55) scale examined four domains of life: cognitive, emotional, social, and physical. Depressed mood and SI were part of the emotional domain. Results The mean ± SD age of children was 8.2 ± 3.25. The mean ± SD of overall QoL was 43.02 ± 15.70, which reflected a poor QoL. Age was not related to the QoL. Female gender was significantly associated with a lower overall QoL (P = 0.0477). Patients with comorbidities had statistically insignificant lower QoL in the cognitive, social, and physical domains in addition to lower overall QoL. Seven of nine participants who reported feeling down reported having SI in the last four weeks (P < 0.001). Conclusions An intractable epilepsy-imposed burden negatively impacts all domains of QoL. Furthermore, females experience lower overall QoL compared to males. Children with comorbidities also tend to have lower QoL scores, although the differences were statistically insignificant. Additionally, a history of feeling down is associated with SI.

show abstract

Section: Discussioncontrasting

confidence: 46%

Quality of Life in Pediatrics With Intractable Epilepsy at King Abdulaziz Medical City, Jeddah, Saudi Arabia: A Cross-Sectional Study

Marghalani¹,

Aljabri²,

Kaneetah³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

“…[ 27 ] Some of the published literature revealed that females are found to have poorer QOL than males. [ 23 28 ] In the current study, associations of the QOL domain scores with the predictors revealed that gender was significantly associated with the social domain, and the total score of QOL where males were significantly associated with a better QOL. In a study that showed the correlation between epilepsy and school attendance, females had a higher percentage of absenteeism.…”

Section: Discussionmentioning

confidence: 50%

Quality of life in paediatrics with intractable epilepsy in a large paediatric university hospital in Riyadh, Saudi Arabia

Altwaijri

Yahya

Alasmari

et al. 2020

J Family Med Prim Care

View full text Add to dashboard Cite

Context: Epilepsy is said to be intractable when two or more trials of anticonvulsants fail to control the seizures. Literature suggests that intractable epilepsy carries a higher morbidity than controlled epilepsy in children and their caregivers. Aims: The aim of this study is to assess the quality of life (QOL) in children with intractable epilepsy (IE) in KASCH, a tertiary care hospital in Riyadh, Saudi Arabia. Settings and Design: This is a cross-sectional study utilizing a self-administered questionnaire filled by caregivers of epileptic patients visiting the outpatient neurology clinics. Methods and Materials: The quality of life in childhood epilepsy (QOLCE-55) scale examined four domains of life: cognitive, emotional, social, and physical. The sample consisted of 59 parents whose children aged 4-14 of either sex. Statistical Analysis Used: The collected data were analyzed by Statistical Package for the Social Sciences (SPSS) version 22. Results: The mean age of children was 8.9 (SD = 2.9). The mean QOL was 52.8 (SD = 12.9), which reflected a poor QOL. Age was not related to the QOL. Gender was significantly associated with the total and social scores, ( P = 0.04) ( P = 0.001), respectively. Out of all comorbidities, global developmental delay (GDD) and encephalopathy were significantly associated with the QOL ( P < 0.05). Conclusions: Intractable epilepsy impacted all functioning domains of life rendering a poor QOL. Males have reported better QOL and social functioning compared to females. Children with GDD and encephalopathy showed lower well-being.

show abstract

“…Srujna et al [ 11 ] observed that gender and age of participants had no relation to the QOL, but factors, such as maternal education and socioeconomic status, strongly correlated with QOL. Haider et al [ 6 ] observed that the type of epilepsy had no relation to QOL, but the patient's age and gender affected QOL. In contrast to other studies, such as Nadkarni et al [ 10 ], they observed that the QOL was more affected in older children with lower socioeconomic status and mothers with lower literacy levels.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, the diagnosis of a chronic illness, such as epilepsy, during childhood is a source of severe stress and poor QOL for the whole family, including parents and siblings [4]. Although few Indian studies [5][6][7][8][9][10][11] have tried to ascertain the QOL of children with epilepsy, there are limited studies on how pediatric epilepsy impacts the QOL of siblings [12][13][14][15]. Hence, we have attempted to assess the QOL of children with epilepsy using epilepsy-specific questionnaires Quality of Life in Childhood Epilepsy Questionnaire-55 (QOLCE-55) and Pediatric Quality of Life Epilepsy Module (Peds QL EM), and the QOL of their siblings was evaluated using the Peds QL Inventory.…”

Section: Introductionmentioning

confidence: 99%

Quality of Life of Developmentally Normal Children With Epilepsy and Their Siblings

Navik,

Aggarwal,

Singh

et al. 2023

Cureus

View full text Add to dashboard Cite

Background: Quality of life (QOL) is a fundamental and multidimensional concept that should be considered with health problems, specifically chronic diseases, such as epilepsy. There have been limited studies on how pediatric epilepsy impacts the QOL of siblings of affected individuals. Hence, we studied the impact of epilepsy on the QOL of affected children and their siblings. Objective: This study aimed to assess the QOL of developmentally normal children with epilepsy and their siblings and the association of QOL scores with the clinicodemographic profile. Methods: This study was conducted at the University College of Medical Sciences and Guru Tegh Bahadur Hospital, New Delhi, India, a tertiary care hospital. The QOL of children (4-12 years) with epilepsy was assessed using epilepsy-specific questionnaires, i.e., Quality of Life in Childhood Epilepsy Questionnaire-55 (QOLCE-55), which covers the cognitive, emotional, social, and physical domains, and Pediatric Quality of Life Epilepsy Module (Peds QL EM), which covers the impact, cognitive, sleep, executive, and mood/ behavior domains. QOL in siblings was assessed using the Peds QL Inventory, which covers the following domains: physical, emotional, social, and school. The principal investigator administered these questionnaires to parents in Hindi/ English. Scoring was done as per standard instructions of the questionnaire. Clinical and demographic data were recorded in a pro forma. Result: The median QOLCE-55 score was 81.12, with a range of 74.65-86.34, and the median Peds QL EM score was 89.31, with a range of 75.58-94.48. Overall, Cronbach's alpha of QOLCE-55 and Peds QL EM was >0.8. Breakthrough seizures (≥10) affected the overall QOL (p=0.001) and all domains of QOLCE-55 (except emotional function (p=0.44)) and Peds QL EM (except sleep/fatigue domain (p=0.59)). Age, sex, parental education, socioeconomic status, and type of epilepsy did not affect the overall QOL (p>0.05). The QOL of siblings was not affected as per the Peds QL Inventory score (median score 100) and self-made questionnaire. Conclusion: Our results suggest that the QOL of children with epilepsy was compromised, whereas the QOL of their siblings was not affected.

show abstract

Quality of Life in Children with Epilepsy in Wah Cantt, Pakistan: A Cross-sectional Study

Cited by 4 publications

References 19 publications

Quality of Life in Pediatrics With Intractable Epilepsy at King Abdulaziz Medical City, Jeddah, Saudi Arabia: A Cross-Sectional Study

Quality of Life in Pediatrics With Intractable Epilepsy at King Abdulaziz Medical City, Jeddah, Saudi Arabia: A Cross-Sectional Study

Quality of life in paediatrics with intractable epilepsy in a large paediatric university hospital in Riyadh, Saudi Arabia

Quality of Life of Developmentally Normal Children With Epilepsy and Their Siblings

Contact Info

Product

Resources

About