Quand Tribolium complémente la génétique de la drosophile

Bonneton, François

doi:10.1051/medsci/2010263297

Cited by 7 publications

(4 citation statements)

References 40 publications

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“…This suggests that the exposure of color patterns have been favored throughout evolution, possibly due to a signaling function. As embryogenesis duration is longer in the Gerromorpha (6–14 d) (23), compared to other insects, such as Drosophila (1 d) or Tribolium castaneum (3 d) (56), it is possible that coloration increases survivorship by allowing the embryos to avoid predation through signaling unpalatability (54). Our ability to manipulate these color patterns provides a good system to test these hypotheses in the future.…”

Section: Discussionmentioning

confidence: 99%

Cooption of the pteridine biosynthesis pathway underlies the diversification of embryonic colors in water striders

Vargas-Lowman

Armisén

Floriano

et al. 2019

Proc. Natl. Acad. Sci. U.S.A.

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Naturalists have been fascinated for centuries by animal colors and color patterns. While widely studied at the adult stage, we know little about color patterns in the embryo. Here, we study a trait consisting of coloration that is specific to the embryo and absent from postembryonic stages in water striders (Gerromorpha). By combining developmental genetics with chemical and phylogenetic analyses across a broad sample of species, we uncovered the mechanisms underlying the emergence and diversification of embryonic colors in this group of insects. We show that the pteridine biosynthesis pathway, which ancestrally produces red pigment in the eyes, has been recruited during embryogenesis in various extraocular tissues including antennae and legs. In addition, we discovered that this cooption is common to all water striders and initially resulted in the production of yellow extraocular color. Subsequently, 6 lineages evolved bright red color and 2 lineages lost the color independently. Despite the high diversity in colors and color patterns, we show that the underlying biosynthesis pathway remained stable throughout the 200 million years of Gerromorpha evolutionary time. Finally, we identified erythropterin and xanthopterin as the pigments responsible for these colors in the embryo of various species. These findings demonstrate how traits can emerge through the activation of a biosynthesis pathway in new developmental contexts.

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Section: Discussionmentioning

confidence: 99%

Cooption of the pteridine biosynthesis pathway underlies the diversification of embryonic colors in water striders

Vargas-Lowman

Armisén

Floriano

et al. 2019

Proc. Natl. Acad. Sci. U.S.A.

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“…By means of a random insertional mutagenesis screen in Tribolium (Trauner et al 2009), a large collection of enhancer-trap and embryonic lethal beetle lines has been made available to the research community, which will facilitate, for the first time in a non-drosophilid arthropod, a large-scale and nonbiased approach to the study of genetic mechanisms underpinning a diverse range of biological traits (Peel 2009). In developmental biology, Tribolium offers a complementary model to Drosophila (Bonneton 2010). …”

Section: Forward Geneticsmentioning

confidence: 99%

Insect omics research coming of age¹This review is part of a virtual symposium on recent advances in understanding a variety of complex regulatory processes in insect physiology and endocrinology, including development, metabolism, cold hardiness, food intake and digestion, and diuresis, through the use of omics technologies in the postgenomic era.

et al. 2012

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As more and more insect genomes are fully sequenced and annotated, omics technologies, including transcriptomic, proteomic, peptidomics, and metobolomic profiling, as well as bioinformatics, can be used to exploit this huge amount of sequence information for the study of different biological aspects of insect model organisms. Omics experiments are an elegant way to deliver candidate genes, the function of which can be further explored by genetic tools for functional inactivation or overexpression of the genes of interest. Such tools include mainly RNA interference and are currently being developed in diverse insect species. In this manuscript, we have reviewed how omics technologies were integrated and applied in insect biology.Résumé : À mesure que de plus en plus de génomes d'insectes sont complètement séquencés et annotés, les technologies « omiques », en particulier la transcriptomique, la protéomique, la peptidomique et le profilage métobolomique, de même que la bioinformatique, peuvent servir à exploiter cet immense quantité d'information séquencée pour l'étude de différents aspects biologiques des organismes modèles entomologiques. Les expériences omiques représentent une voie élégante pour fournir des gènes candidats dont la fonction peut être encore explorée plus avant à l'aide des outils génétiques d'inactivation fonctionnelle ou de surexpression des gènes retenus. Ces outils comprennent surtout l'ARN interférent et sont en train d'être mis au point pour diverses espèces d'insectes. Nous passons en revue dans notre présentation comment les technologies omiques ont été intégrées dans la biologie des insectes et comment on les a utilisées.

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“…The question of trans-metamorphic memory, postulated nearly a century ago, remains unsolved yet ripe for study given the development of molecular tools for model species such as Tribolium . 53,54 …”

Section: Introductionmentioning

confidence: 99%

The stability of memories during brain remodeling: A perspective

Blackiston

Shomrat

Levin

2015

Communicative & Integrative Biology

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One of the most important features of the nervous system is memory: the ability to represent and store experiences, in a manner that alters behavior and cognition at future times when the original stimulus is no longer present. However, the brain is not always an anatomically stable structure: many animal species regenerate all or part of the brain after severe injury, or remodel their CNS toward a new configuration as part of their life cycle. This raises a fascinating question: what are the dynamics of memories during brain regeneration? Can stable memories remain intact when cellular turnover and spatial rearrangement modify the biological hardware within which experiences are stored? What can we learn from model species that exhibit both, regeneration and memory, with respect to robustness and stability requirements for long-term memories encoded in living tissues? In this Perspective, we discuss relevant data in regenerating planaria, metamorphosing insects, and hibernating ground squirrels. While much remains to be done to understand this remarkable process, molecular-level insight will have important implications for cognitive science, regenerative medicine of the brain, and the development of non-traditional computational media in synthetic bioengineering.

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Quand Tribolium complémente la génétique de la drosophile

Cited by 7 publications

References 40 publications

Cooption of the pteridine biosynthesis pathway underlies the diversification of embryonic colors in water striders

Cooption of the pteridine biosynthesis pathway underlies the diversification of embryonic colors in water striders

The stability of memories during brain remodeling: A perspective

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