Quantification of Interpoint Topographic Correlations of Threshold Values in Glaucomatous Visual Fields

Rosa, Manuel Gonzalez-de-la; Abraldes, Maximino; González-Hernández, Marta; Azuara‐Blanco, Augusto

doi:10.1097/00061198-200202000-00007

Cited by 21 publications

(6 citation statements)

References 15 publications

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“…A higher sensitivity using SITA was only present at five stimulus locations in the temporal field. This region also yielded the lowest mean bias when assessing the six regions described by de la Rosa et al, 29 but we are unable to provide an explanation for this finding. In conclusion, the clinical examination of normal subjects using SPARK Precision yields a sensitivity profile across the visual field which is similar to SITA Standard but in a relatively faster examination time.…”

Section: Discussioncontrasting

confidence: 72%

Comparison between two fast threshold strategies: SPARK and SITA in normal subjects

Foo

Cubbidge

Heitmar

2020

European Journal of Ophthalmology

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Background Numerous fast threshold strategies have been developed in perimetry which use maximum likelihood approaches to estimate the threshold. A recent approach to threshold estimation has been developed estimating the threshold from a limited number of test points which further reduces examination time. This strategy, SPARK, has not been compared to the SITA strategy. The aim of this study was to compare SPARK with SITA in a normal cohort to evaluate within and between strategy agreement in threshold estimates. Methods A total of 83 normal subjects each underwent two visual field examinations with SITA and SPARK on two separate occasions on a randomly selected eye. The eye examined and the order of strategy examined first was randomised but remained constant over the two perimetry visits. Results Visual field examination with SPARK Precision was on average 33% faster than SITA Standard. A positive correlation between group mean sensitivities of SITA Standard and SPARK Precision (rho = 0.713, p < 0.001) was found. In total, 95% of stimulus locations were located within the 95% limits of agreement and linear regression on the differences in sensitivities showed no statistically significant proportional bias (t = 1.713, p = 0.09). Pointwise analysis showed SITA Standard had significantly larger variability for individual stimulus locations examined over two visits when compared to SPARK (t = 9.175, p < 0.001). Conclusion The clinical examination of SPARK yields a sensitivity profile similar to SITA but in a faster examination time. The lower threshold variability of SPARK may be as a result of data smoothing in the threshold estimation process.

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Section: Discussioncontrasting

confidence: 72%

Comparison between two fast threshold strategies: SPARK and SITA in normal subjects

Foo

Cubbidge

Heitmar

2020

European Journal of Ophthalmology

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“…This experience would be correct if they did not ignore the intense physiopathological dependences between the different regions of the glaucomatous visual field [25]. Its results only reflect that the model used is not correct, because the real glaucoma visual field is not made up by defects of arbitrary location and deepness like the ones used in this paper.…”

Section: Discussionmentioning

confidence: 91%

Comparison of Diagnostic Ability between a Fast Strategy, Tendency-Oriented Perimetry, and the Standard Bracketing Strategy

González-Hernández

Morales²,

Azuara‐Blanco

et al. 2005

Ophthalmologica

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Purpose: To compare the diagnostic abilities of the standard bracketing strategy (BR) and a fast strategy, the tendency-oriented perimetry (TOP). Methods: Seventy-seven controls and 91 eyes from patients with glaucoma were analyzed with the strategies TOP and BR. Sensitivity (Se), specificity (Sp), the area under the receiver operating characteristic (ROC) curve (AC) and the optimum cutoff value (CO) were calculated for the visual field indices mean defect (MD), the square root of the loss variance (sLV) and the number of pathological points (NPP). Results: In the glaucoma group, the mean MD value using TOP and BR was 7.5 and 8.3 dB, respectively. The mean sLV value using TOP and BR was 5.0 and 5.3 dB, respectively. Indices provided by TOP had higher ROC values than the ones provided by BR. Using TOP, the index with the best diagnostic ability was sLV (Sp = 94.8, Se = 90.1, AC = 0.966, CO = 2.5 dB), followed by NPP and MD. Using BR, the best results were obtained for MD (Sp = 92.2, Se = 81.3, AC = 0.900, CO = 2.5 dB) followed by sLV and NPP. Conclusions: A fast strategy, TOP, had superior diagnostic ability than the standard BR. Although TOP provided lower LV values than BR, the diagnostic ability of this index was higher than that of the conventional strategy.

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“…The use of relatively large truncated quadrants may suggest intuitively that localisation of visual loss was being sacrificed though there is evidence to suggest that this is not the case. Threshold values between neighbouring test points tend to be correlated with the result that the central visual field is organized into discrete clusters or sectors which are related to the projection of retinal ganglion cell axons [34,35]. Another issue is the variation in the number of cycles between superior/inferior and nasal/temporal truncated quadrants.…”

Section: Discussionmentioning

confidence: 99%

Relationship between visual field loss and contrast threshold elevation in glaucoma

Tochel

Morton

et al. 2005

BMC Ophthalmol

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BackgroundThere is a considerable body of literature which indicates that contrast thresholds for the detection of sinusoidal grating patterns are abnormally high in glaucoma, though just how these elevations are related to the location of visual field loss remains unknown. Our aim, therefore, has been to determine the relationship between contrast threshold elevation and visual field loss in corresponding regions of the peripheral visual field in glaucoma patients.MethodsContrast thresholds were measured in arcuate regions of the superior, inferior, nasal and temporal visual field in response to laser interference fringes presented in the Maxwellian view. The display consisted of vertical green stationary laser interference fringes of spatial frequency 1.0 c deg-1 which appeared in a rotatable viewing area in the form of a truncated quadrant extending from 10 to 20° from fixation which was marked with a central fixation light. Results were obtained from 36 normal control subjects in order to provide a normal reference for 21 glaucoma patients and 5 OHT (ocular hypertensive) patients for whom full clinical data, including Friedmann visual fields, had been obtained.ResultsAbnormally high contrast thresholds were identified in 20 out of 21 glaucoma patients and in 2 out of 5 OHT patients when compared with the 95% upper prediction limit for normal values from one eye of the 36 normal age-matched control subjects. Additionally, inter-ocular differences in contrast threshold were also abnormally high in 18 out of 20 glaucoma patients who had vision in both eyes compared with the 95% upper prediction limit. Correspondence between abnormally high contrast thresholds and visual field loss in the truncated quadrants was significant in 5 patients, borderline in 4 patients and absent in 9 patients.ConclusionWhile the glaucoma patients tested in our study invariably had abnormally high contrast thresholds in one or more of the truncated quadrants in at least one eye, reasonable correspondence with the location of the visual field loss only occurred in half the patients studied. Hence, while contrast threshold elevations are indicative of glaucomatous damage to vision, they are providing a different assessment of visual function from conventional visual field tests.

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Quantification of Interpoint Topographic Correlations of Threshold Values in Glaucomatous Visual Fields

Cited by 21 publications

References 15 publications

Comparison between two fast threshold strategies: SPARK and SITA in normal subjects

Comparison between two fast threshold strategies: SPARK and SITA in normal subjects

Comparison of Diagnostic Ability between a Fast Strategy, Tendency-Oriented Perimetry, and the Standard Bracketing Strategy

Relationship between visual field loss and contrast threshold elevation in glaucoma

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