Quantification of regional left and right ventricular radial and longitudinal function in healthy children using ultrasound-based Strain Rate and Strain Imaging

Weidemann, Frank; Eyskens, Bénédicte; Jamal, F; Mertens, Luc; Kowalski, Mirosław; D'hooge, Jan; Bijnens, Bart; Gewillig, Marc; Rademakers, Frank; Hatle, Liv; Sutherland, George R.

doi:10.1067/mje.2002.116532

Cited by 203 publications

(150 citation statements)

References 27 publications

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“…65 Normative deformation values for healthy children are available. 66 Deformation imaging has also been performed in healthy and asphyxiated neonates. [67][68][69] Reduced longitudinal RV deformation has been shown in patients with congenitally corrected transposition of the great arteries suffering from increased RV afterload.…”

Section: Rv Fractional Area Changementioning

confidence: 99%

Transthoracic Echocardiography in the Evaluation of Pediatric Pulmonary Hypertension and Ventricular Dysfunction

et al. 2016

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Transthoracic echocardiography (TTE) is the most accessible noninvasive diagnostic procedure for the initial assessment of pediatric pulmonary hypertension (PH). This review focuses on principles and use of TTE to determine morphologic and functional parameters that are also useful for follow-up investigations in pediatric PH patients. A basic echocardiographic study of a patient with PH commonly includes the hemodynamic calculation of the systolic pulmonary artery pressure (PAP), the mean and diastolic PAP, the pulmonary artery acceleration time, and the presence of a pericardial effusion. A more detailed TTE investigation of the right ventricle (RV) includes assessment of its size and function. RV function can be evaluated by RV longitudinal systolic performance (e.g., tricuspid annular plane systolic excursion), the tricuspid regurgitation velocity/right ventricular outflow tract velocity time integral ratio, the fractional area change, tissue Doppler imaging-derived parameters, strain measurements, the systolic-to-diastolic duration ratio, the myocardial performance (Tei) index, the RV/left ventricle (LV) diameter ratio, the LV eccentricity index, determination of an enlarged right atrium and RV size, and RV volume determination by 3-dimensional echocardiography. Here, we discuss the potential use and limitations of TTE techniques in children with PH and/or ventricular dysfunction. We suggest a protocol for TTE assessment of PH and myocardial function that helps to identify PH patients and their response to pharmacotherapy. The outlined protocol focuses on the detailed assessment of the hypertensive RV; RV-LV crosstalk must be analyzed separately in the evaluation of different pathologies that account for pediatric PH.

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Section: Rv Fractional Area Changementioning

confidence: 99%

Transthoracic Echocardiography in the Evaluation of Pediatric Pulmonary Hypertension and Ventricular Dysfunction

et al. 2016

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“…During this process, frame rate was increased by narrowing the sector angle to 15-30° and the wall to be recorded was positioned in the center of the sector to minimize the artifacts and then it was re-aligned so as to achieve a parallel direction of the evaluated motion as near to the direction of the insonating beam as possible (25). From these records, by using Echopac PC software program, S and SR parameters were calculated from LA mid and superior segments of lateral wall, interatrial septum, anterior and lateral walls during each mechanical period (10,26,27) (Fig.…”

Section: Assessment Of Mitral Regurgitationmentioning

confidence: 99%

Quantitative assessment of the left atrial myocardial deformation in patients with chronic mitral regurgitation by strain and strain rate imaging: an observational study

Aksakal¹,

Şimşek²,

Sevimli³

et al. 2012

Anadolu Kardiyol Derg

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“…To assess radial function of the posterior wall, parasternal long-axis views were used. 6 CDMI data were analyzed using dedicated software (TVI, GE Ultrasound). 6 Longitudinal strain rates in the basal, mid, and apical segments of each wall and radial strain rates of the posterior wall were estimated by measuring the spatial velocity gradient.…”

Section: Color Doppler Myocardial Imagingmentioning

confidence: 99%

“…6 CDMI data were analyzed using dedicated software (TVI, GE Ultrasound). 6 Longitudinal strain rates in the basal, mid, and apical segments of each wall and radial strain rates of the posterior wall were estimated by measuring the spatial velocity gradient. Strain rate profiles were averaged over 3 consecutive cardiac cycles and integrated over time to derive natural strain profiles using end-diastole as the reference point (Speqle).…”

Section: Color Doppler Myocardial Imagingmentioning

confidence: 99%

Improvement of Cardiac Function During Enzyme Replacement Therapy in Patients With Fabry Disease

Weidemann¹,

Breunig²,

Beer³

et al. 2003

Circulation

Self Cite

359

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Background-Enzyme replacement therapy (ERT) has been shown to enhance microvascular endothelial globotriaosylceramide clearance in the hearts of patients with Fabry disease. Whether these results can be translated into an improvement of myocardial function has yet to be demonstrated. Methods and Results-Sixteen patients with Fabry disease who were treated in an open-label study with 1.0 mg/kg body weight of recombinant ␣-Gal A (agalsidase ␤, Fabrazyme) were followed up for 12 months. Myocardial function was quantified by ultrasonic strain rate imaging to assess radial and longitudinal myocardial deformation. End-diastolic thickness of the left ventricular posterior wall and myocardial mass (assessed by magnetic resonance imaging, nϭ10) was measured at baseline and after 12 months of ERT. Data were compared with 16 age-matched healthy controls. At baseline, both peak systolic strain rate and systolic strain were significantly reduced in the radial and longitudinal direction in patients compared with controls. Peak systolic strain rate increased significantly in the posterior wall (radial function) after one year of treatment (baseline,

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Quantification of regional left and right ventricular radial and longitudinal function in healthy children using ultrasound-based Strain Rate and Strain Imaging

Cited by 203 publications

References 27 publications

Transthoracic Echocardiography in the Evaluation of Pediatric Pulmonary Hypertension and Ventricular Dysfunction

Transthoracic Echocardiography in the Evaluation of Pediatric Pulmonary Hypertension and Ventricular Dysfunction

Quantitative assessment of the left atrial myocardial deformation in patients with chronic mitral regurgitation by strain and strain rate imaging: an observational study

Improvement of Cardiac Function During Enzyme Replacement Therapy in Patients With Fabry Disease

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