Quantification of the left ventricular volumes and function with cine MR imaging: comparison of geometric models with three-dimensional data.

Abstract

Acquisition and measurement of left ventricular (LV) volumes with a three-dimensional data set of cine magnetic resonance (MR) images from apex to base is a time-consuming process. Results of a study with 10 healthy volunteers and 10 patients with LV hypertrophy were prospectively evaluated. The heart was shown in the anatomic short- and horizontal long-axis planes with cine MR imaging. LV volumes were measured with various geometric models, and ejection fractions were calculated. In both groups, the values of LV stroke volume obtained with a modified Simpson rule and biplane ellipsoid models correlated well to the analysis of the three-dimensional data set of cine MR images. There were no significant differences for the calculated ejection fraction between values obtained with the modified Simpson rule or the biplane ellipsoid model versus the three-dimensional data set. A high inter-observer reproducibility of cine MR measurements with the two former models was found. Therefore, modified Simpson rule and biplane ellipsoid models, with their shorter acquisition and processing times, may increase the clinical utility of cine MR imaging.

Very acute cardiac toxicity during BEAC chemotherapy in non-Hodgkin's lymphoma patients undergoing autologous stem cell transplantation

“…Left ventricular end-systolic (ESV) and end-diastolic (EDV) volumes were calculated using the modified Simpson's rule. 16,17 LVEF was calculated using the equation LVEF ¼ ((EDVÀESV)/EDV) Â 100%. 16 All MRI studies and image analysis were performed by one investigator (MH-S).…”

“…16,17 LVEF was calculated using the equation LVEF ¼ ((EDVÀESV)/EDV) Â 100%. 16 All MRI studies and image analysis were performed by one investigator (MH-S). In this study, LVEF decrease X10% from the baseline or LVEFo50% were defined as abnormal.…”

“…The whole blood was centrifuged and plasma immediately frozen and stored at À701C. Circulating NT-proBNP (antiserum to NT-proBNP [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29] ) and NT-proANP (antiserum to NT-proANP 46-79 ) concentrations were determined by radioimmunoassays as previously described. Molecular heterogeneity has a major impact on the measurement of circulating N-terminal fragments of A-and B-type natriuretic peptides.…”

Evaluation of Left and Right Ventricular Ejection Fraction and Volumes from Gated Blood-Pool SPECT in Patients with Dilated Cardiomyopathy: Comparison with Cardiac MRI

“…All sets of drawings were reviewed by a CMR expert who had no access to the GBPS data. CMR values were computed by the modified Simpson rule (24).…”

The role of imaging and molecular imaging in the early detection of metabolic and cardiovascular dysfunctions

“…This could be time-consuming, more particularly, if the entire heart volume is acquired. The modified Simpson's method allows the measurement of the left ventricular ejection fraction with high accuracy compared with the full three-dimensional reconstruction method 15 (Figure 3a). The modified Simpson's method consists of acquiring two short-axis views and one long-axis view, hence reducing acquisition (and analysis) time, when compared with full coverage of the LV.…”