This study investigates the relationship of personal characteristics for online entrepreneur, internal environment and external environment to the orientation online entrepreneur and business performance. This study also analyzed the role of web quality on the relationship of business orientation and entrepreneurial performance. Data used are primary data, collected through questionnaires to online entrepreneurship students at 4 Universities in Jakarta, Bogor, Depok, Tangerang and Bekasi. The sample size taken is 273 online entrepreneurship students. Data processed descriptively, and using SEM (Structural Equation Modeling) AMOS 23 Program. The results indicate that the characteristics of personal, internal environment and external environment have a positive effect on the orientation of the online entrepreneur. Furthermore, the online student orientation has a positive effect on the performance with the quality of the web as a moderating variable.