2024
DOI: 10.1101/2024.03.18.585599
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Quantitating SARS-CoV-2 Neutralizing Antibodies from Human Dried Blood Spots

Katherine Berman,
Greta Van Slyke,
Hayley Novak
et al.

Abstract: Background: In the earliest days of COVID-19 pandemic, the collection of dried blood spots (DBS) enabled public health laboratories to undertake population-scale seroprevalence studies to estimate rates of SARS-CoV-2 exposure. With SARS-CoV-2 seropositivity levels now estimated to exceed 94% in the United States, attention has turned to using DBS to assess functional (neutralizing) antibodies within cohorts of interest. Methods: Contrived DBS eluates from convalescent, fully vaccinated and pre-COVID-19 serum s… Show more

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