Quantitative alterations in intramuscular connective tissue following immobilization: An experimental study in the rat calf muscles

Józsa, László; Thöring, J; Järvinen, Markku; Kannus, Pekka; Lehto, Matti; Kvist, M

doi:10.1016/0014-4800(88)90039-1

Cited by 70 publications

(43 citation statements)

References 15 publications

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“…The skeletal muscle tissue is composed primarily of contractile components and there is also a close association between these elements and the muscle connective tissue (CT). Thus, the elastic behavior of skeletal muscle is determined not only by the contractile components, but also by this second tissue [34]. In skeletal muscle, 1-10% of its mass is formed by connective tissue, and this percentage varies between muscles with different functions [35,6].…”

Section: Clinical Aspects Of Immobilizationmentioning

confidence: 99%

Consequences of immobilization and disuse: a short review

Júnior

Nonato

Cavalcante

et al. 2013

International Journal of Basic and Applied Sciences

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Immobilization and disuse of a body part is quite common in the rehabilitation of patients suffering from injuries or diseases. There are a number of deleterious effects, including systems and organs such as the respiratory, cardiac and skeletal muscle. The clinical and physiological principal aspects revised in this short review are: muscular atrophy, general metabolic alterations, increase of connective tissue, muscular power loss, oxidative stress, loss of weight and neural changes. We conclude that immobilization/disuse should be evaluated and questioned if we really have indicated before being prescribed, as this causes many physiological and clinical deleterious effects.

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Section: Clinical Aspects Of Immobilizationmentioning

confidence: 99%

Consequences of immobilization and disuse: a short review

Júnior

Nonato

Cavalcante

et al. 2013

International Journal of Basic and Applied Sciences

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“…Furthermore Shelboune and colleagues have shown that even small losses of 3-5°of extension can significantly affect outcomes following cruciate reconstruction [42•]. It is clear that extended immobilization of the knee is detrimental to structures that surround the knee including ligaments, cartilage, bone and muscles [37,[43][44][45][46][47][48]. If a patient has had additional procedures such as a meniscus repair, knee flexion will be limited to 90°for 4 weeks.…”

Section: Introductionmentioning

confidence: 99%

Recent advances following anterior cruciate ligament reconstruction: rehabilitation perspectives

Manske

Prohaska

Lucas

2012

Curr Rev Musculoskelet Med

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Injuries to the anterior cruciate ligament are common. Surgical reconstruction is more prevalent than ever. This review article discusses treatment of the patient following surgical reconstruction of the anterior cruciate ligament. Various phases of rehabilitation are discussed with emphasis on early return of passive motion, early weight bearing, bracing, kinetic chain exercises, neuromuscular electrical stimulation and accelerated rehabilitation. Although evidence exists for the treatment of the surgically reconstructed cruciate ligament, more is needed to better define specific timeframes for advancement. Evidence exists that many of these young individuals are not fully returning to unlimited high level activities. This review article presents some of the latest evidence regarding anterior cruciate ligament rehabilitation in an attempt to help the busy clinician understand and relate basic and clinical research to rehabilitation of a patient following reconstruction.

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“…Alguns autores sugerem que a maioria das mudanças ocorre nos primeiros sete dias 5,6,12 . Porém, outros trabalhos demonstram atrofia significativa no período de 14 dias em diferentes modelos de desuso muscular 1,13 .…”

Section: Introductionunclassified

Efeitos da estimulação elétrica neuromuscular sobre o membro posterior imobilizado de ratos durante 15 dias: análises metabólicas e morfométricas

Durigan¹,

Cancelliero²,

Dias³

et al. 2006

Rev. bras. fisioter.

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RESUMOObjetivo: Avaliar o efeito da estimulação elétrica (EE) sobre o perfil metabólico e morfométrico dos músculos do membro posterior de ratos submetidos à imobilização durante 15 dias. Método: Ratos Wistar foram divididos em 3 grupos (n=5): controle, imobilizado por 15 dias e imobilizado associado à EE por 15 dias. Foram avaliados: reserva de glicogênio (RG) dos músculos sóleo (S), extensor longo dos dedos (ELD), gastrocnêmio branco (GB), gastrocnêmio vermelho (GV) e tibial anterior (TA), além do peso do sóleo, área das fibras e tecido conjuntivo do S. A análise estatística foi feita pelos testes ANOVA e Kruskal-Wallis (p<0,05). Resultados: A imobilização promoveu alterações significativas (p<0,05) como: redução nas RG (S: 44,73%, GB: 47,82%, GV: 46,34%, ELD: 41,66%, TA: 48,38%), no peso (7,2%) e na área das fibras (35%) do S, além do aumento da densidade do tecido conjuntivo (160%). A EE promoveu aumento significativo (p<0,05) nas RG de todos os músculos imobilizados (S: 90,47%, GB: 62,5%, GV: 95,45%, ELD: 76,19%, TA: 56,25%), no peso (20,94%) e na área das fibras (19,65%) do S e também promoveu redução significativa (15,38%, p<0,05) na densidade do tecido conjuntivo. Conclusões: A EE minimizou a redução das RG, preveniu a redução da área das fibras e a proliferação do tecido conjuntivo nos músculos submetidos à imobilização.Palavras-chave: estimulação elétrica, imobilização, morfometria, metabolismo, fisioterapia. ABSTRACT Effects of Neuromuscular Electrical Stimulation on Rat Hind Limbs Immobilized for 15 Days: Metabolic and Morphometric AnalysesObjective: To evaluate the effect of electrical stimulation on the metabolic and morphometric profile of rat hind limb muscles subjected to immobilization for 15 days. Method: Wistar rats were divided into three groups (n=5): control; immobilized for 15 days; and immobilized for 15 days with electrical stimulation. The glycogen reserves of the soleus, extensor digitorum longus (EDL), white gastrocnemius (WG), red gastrocnemius (RG) and tibialis anterior (TA) muscles were evaluated, along with the weight, fibrous area and conjunctive tissue of the soleus.

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Quantitative alterations in intramuscular connective tissue following immobilization: An experimental study in the rat calf muscles

Cited by 70 publications

References 15 publications

Consequences of immobilization and disuse: a short review

Consequences of immobilization and disuse: a short review

Recent advances following anterior cruciate ligament reconstruction: rehabilitation perspectives

Efeitos da estimulação elétrica neuromuscular sobre o membro posterior imobilizado de ratos durante 15 dias: análises metabólicas e morfométricas

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