Quantitative determination of diterpene acids in garden sage leaves

Khaliullina, A. S.; Хазиев, Р. Ш.; Salamatin, A. A.

doi:10.1134/s1061934817070073

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…Two less-explored techniques that were applied for the analysis of diterpenes such as carnosic acid are UV spectrophotometry and square-wave voltammetry (SWV) [98,99]. The former was utilized for the quantitative determination of the diterpenes extracted from garden sage leaves.…”

Section: Capillary Electrophoresis (Ce) and Other Techniquesmentioning

confidence: 99%

“…The former was utilized for the quantitative determination of the diterpenes extracted from garden sage leaves. The measured concentrations of diterpenes at 285 nm, ranged from 2.1 to 3.6% in terms of carnosic acid [98]. Yilmaz et al studied the electrochemical behavior of carnosic acid and based on their findings, developed a square-wave voltammetric method for the determination of carnosic acid in rosemary extracts.…”

Section: Capillary Electrophoresis (Ce) and Other Techniquesmentioning

confidence: 99%

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Carnosic Acid and Carnosol: Analytical Methods for Their Determination in Plants, Foods and Biological Samples

Mantzourani,

Tarantilis,

Kokotou

2023

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Among the various phytochemicals, which are present in Lamiaceae plants, carnosic acid and carnosol stand out. Carnosic acid is a phenolic diterpene carrying two phenolic hydroxyl groups and a carboxyl group, while carnosol carries a lactone moiety in addition to phenolic hydroxyls. Both these phenolic diterpenes exhibit interesting biological properties, such as antioxidant, anticancer, anti-inflammatory and neuroprotective activities. In this review, we summarize the existing analytical methods for the determination of carnosic acid and carnosol, primarily in plants, but also in foods and biological samples. Due to the biological importance of carnosic acid and carnosol, a variety of analytical methods, including high-performance liquid chromatography–ultra violet (HPLC–UV), liquid chromatography–mass spectrometry (LC–MS) and capillary electrophoresis (CE), were developed for their determination. In addition, we discuss the extraction methods applied for their isolation from plants and in brief the bioactivities of these phytochemicals.

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Section: Capillary Electrophoresis (Ce) and Other Techniquesmentioning

confidence: 99%

Section: Capillary Electrophoresis (Ce) and Other Techniquesmentioning

confidence: 99%