Quantitative light-induced fluorescence (QLF): A tool for early occlusal dental caries detection and supporting decision making in vivo

Alammari, Manal R; Smith, Philip W.; Jong, Elbert de Josselin de; Higham, Susan

doi:10.1016/j.jdent.2012.08.013

Cited by 74 publications

(54 citation statements)

References 21 publications

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“…Quantitative light-induced fluorescence (QLF) is known as an imaging technique with the option to visualize present bacterial activity in carious lesions [11,47]. The method is based on autofluorescence of tooth hard tissues and quantifies the autofluorescence difference between sound and carious (pathogenic) enamel.…”

Section: Caries Diagnosismentioning

confidence: 99%

“…X-ray diagnosis, in particular, has limitations and drawbacks: the exposure to ionizing radiation, the interpretation failures due to superpositioning effects, and a low sensitivity [10] that hinders the early detection and monitoring of minor pathological changes. Recently, innovative methods based on fluorescence [11], impedance spectroscopy, or digital infrared-transillumination have been implemented in caries diagnosis [12]. However, even these techniques were not able to solve the referred challenges and showed deficits in both sensitivity and specificity [1,13].…”

Section: Introductionmentioning

confidence: 99%

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Dental Applications of Optical Coherence Tomography (OCT) in Cariology

et al. 2017

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Across all medical disciplines, therapeutic interventions are based on previously acquired diagnostic information. In cariology, which includes the detection and assessment of the disease "caries" and its lesions, as well as non-invasive to invasive treatment and caries prevention, visual inspection and radiology are routinely used as diagnostic tools. However, the specificity and sensitivity of these standard methods are still unsatisfactory and the detection of defects is often afflicted with a time delay. Numerous novel methods have been developed to improve the unsatisfactory diagnostic possibilities in this specialized medical field. These newer techniques have not yet found widespread acceptance in clinical practice, which might be explained by the generated numerical or color-coded output data that are not self-explanatory. With optical coherence tomography (OCT), an innovative image-based technique has become available that has considerable potential in supporting the routine assessment of teeth in the future. The received cross-sectional images are easy to interpret and can be processed. In recent years, numerous applications of OCT have been evaluated in cariology beginning with the diagnosis of different defects up to restoration assessment and their monitoring, or the visualization of individual treatment steps. Based on selected examples, this overview outlines the possibilities and limitations of this technique in cariology and restorative dentistry, which pertain to the most clinical relevant fields of dentistry.

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Section: Caries Diagnosismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Dental Applications of Optical Coherence Tomography (OCT) in Cariology

et al. 2017

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“…A UV filter of a spectrophotometer was adjusted to change the UV component of the illuminant D65. From the spectral reflectance values, subtraction spectra between the spectra in UVincluded conditions (20,40,60,80, and 100%) and that in the 0% UV condition of the illuminant D65 were calculated. The fluorescence parameter between each of the UV-included conditions and the 0% UV condition was also calculated.…”

Section: Fluorescence Of Dental Restorative Materials and Its Signifimentioning

confidence: 99%

“…It was determined whether QLF parameters, ΔF and ΔQ, were appropriate for aiding diagnosis and clinical decision making of early occlusal mineral loss by comparing QLF analysis with actual restorative management. 60 DIAGNOdent (DD; KavoDental GmbH, Germany) uses a laser to excite fluorescence from pigments in carious tooth structure. 61 The correlation between DD readings and the extent of incipient occlusal caries as measured by the volume of tooth preparation in vitro was evaluated.…”

Section: Fluorescence Of Dental Cariesmentioning

confidence: 99%

Fluorescence properties of human teeth and dental calculus for clinical applications

Lee¹

2015

J. Biomed. Opt

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Abstract. Fluorescent emission of human teeth and dental calculus is important for the esthetic rehabilitation of teeth, diagnosis of dental caries, and detection of dental calculus. The purposes of this review were to summarize the fluorescence and phosphorescence of human teeth by ambient ultraviolet (UV) light, to investigate the clinically relevant fluorescence measurement methods in dentistry, and to review the fluorescence of teeth and dental calculus by specific wavelength light. Dentine was three times more phosphorescent than enamel. When exposed to light sources containing UV components, the fluorescence of human teeth gives them the quality of vitality, and fluorescent emission with a peak of 440 nm is observed. Esthetic restorative materials should have fluorescence properties similar to those of natural teeth. Based on the fluorescence of teeth and restorative materials as determined with a spectrophotometer, a fluorescence parameter was defined. As to the fluorescence spectra by a specific wavelength, varied wavelengths were investigated for clinical applications, and several methods for the diagnosis of dental caries and the detection of dental calculus were developed. Since fluorescent properties of dental hard tissues have been used and would be expanded in diverse fields of clinical practice, these properties should be investigated further, embracing newly developed optical techniques.

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“…Using this QLF system, quantification of the mineral loss or remineralization can be measured 26) . QLF can observe non-cavity dental caries and initial dental caries lesion, and show the excellent ability of early detection of dental caries 27,28) .…”

Section: Discussionmentioning

confidence: 99%

Remineralization ability of fluoride varnish containing tricalcium phosphate by time

Cho

Lee

et al. 2017

J Korean Acad Oral Health

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This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.Objectives: The aim of this study was to evaluate the degree of remineralization over time after application of fluoride varnish with and without tricalcium phosphate (TCP). Methods: This in vitro study used extracted bovine lateral incisors without dental caries. Artificial lesions were created in the enamel specimens. The amount of mineral loss (DF before ) was measured using quantitative light-induced fluorescence (QLF). Test fluoride varnishes (10 mg) were applied to the enamel surface of the specimen and dried for 4 min. No fluoride varnish was applied to the specimens in the control group. Each group was randomly assigned 12 specimens, and remineralization was allowed to occur to different time points (0.5, 1, 3, 6, 12, and 24 h) in each group. Specimens were washed with distilled water and dried with compressed air for 3 s. DF after was determined using QLF. Results: When fluoride varnish containing TCP was applied for up to 6 h, the amount of mineral loss significantly increased, and when non-TCP fluoride varnish was applied for up to 12 hours, the amount of mineral loss significantly increased (P<0.05). However, the amount of mineral loss was higher in the control group. The difference between DF before and DF after (DDF) increased over time. There was a significant difference between the TCP group and the control group after 6 h. The non-TCP group showed a significant difference after 24 h compared to the control group. After 12 h, significant differences were observed in the TCP group compared to both the non-TCP and control groups. Conclusions: This study showed that the degree of remineralization increased gradually over time after fluoride varnish application compared to the control group. In particular, fluoride varnish containing TCP showed better remineralization capability than varnish without TCP.

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Quantitative light-induced fluorescence (QLF): A tool for early occlusal dental caries detection and supporting decision making in vivo

Cited by 74 publications

References 21 publications

Dental Applications of Optical Coherence Tomography (OCT) in Cariology

Dental Applications of Optical Coherence Tomography (OCT) in Cariology

Fluorescence properties of human teeth and dental calculus for clinical applications

Remineralization ability of fluoride varnish containing tricalcium phosphate by time

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