Quantum Dots for Pharmaceutical and Biomedical Analysis

Kara, Hayriye Eda Şatana; Ertaş, Nusret

doi:10.5772/intechopen.70034

Cited by 6 publications

(4 citation statements)

References 132 publications

(128 reference statements)

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“…The electroluminescence and optical properties of the QD core can be manipulated by altering the sizes of the QD core and shell. Furthermore, core/shell QDs having a shell band gap larger than the core band gap give rise to the electroluminescence properties related to exciton decay by radiative processes [ 56 , 57 ].…”

Section: Structural and Optical Properties Of Qdsmentioning

confidence: 99%

“…Thus, a light source with a wavelength shorter than the emission wavelength can lead to multiple excitations (and emissions) because of its broad absorption band. These properties that QDs exhibit, broad excitation spectra and narrow emission spectra [ 57 ], make them suitable for multiplexed imaging [ 58 , 59 ]. Figure 2 names some optical properties of QDs.…”

Section: Structural and Optical Properties Of Qdsmentioning

confidence: 99%

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Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes

Hamidu,

Pitt,

Husseini

2023

Nanomaterials

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Cancer is one of the leading causes of death worldwide. Because each person’s cancer may be unique, diagnosing and treating cancer is challenging. Advances in nanomedicine have made it possible to detect tumors and quickly investigate tumor cells at a cellular level in contrast to prior diagnostic techniques. Quantum dots (QDs) are functional nanoparticles reported to be useful for diagnosis. QDs are semiconducting tiny nanocrystals, 2–10 nm in diameter, with exceptional and useful optoelectronic properties that can be tailored to sensitively report on their environment. This review highlights these exceptional semiconducting QDs and their properties and synthesis methods when used in cancer diagnostics. The conjugation of reporting or binding molecules to the QD surface is discussed. This review summarizes the most recent advances in using QDs for in vitro imaging, in vivo imaging, and targeted drug delivery platforms in cancer applications.

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Section: Structural and Optical Properties Of Qdsmentioning

confidence: 99%

Section: Structural and Optical Properties Of Qdsmentioning

confidence: 99%

Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes

Hamidu,

Pitt,

Husseini

2023

Nanomaterials

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“…Effect of cationic proteins on gold nanoparticles-Aptamer Essays is another method for basis of construction of Biosensor. Biosensors based on aggregation of gold nanoparticles employing small molecules such as CBD and CBN is possible (Kang et al, 2015;Kara and Ertaş, 2017;Pawar et al, 2018;Rizvi et al, 2010;Rosenthal et al, 2011).…”

Section: Nanotechnology and Phytocannabinoidsmentioning

confidence: 99%

Therapeutic Potential of Cannabis Plant

Pote,

Khurana,

Kaur

et al. 2023

IJPE

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The aim of this review article is to outline the role of the plant Cannabis sativa in treating human ailments. Giant pharmaceuticalcompanies are marketing phytochemicals extracted from Cannabis plant and its derivatives to treat epilepsy and multiple sclerosis.The present review emphasizes cannabinoids – its derivatives and synthetic analogs – as an active pharmaceutical Ingredient to treatailments related to autoimmune human body responses. The endocannabinoid system CB1 and CB2 respond differently to variousphytochemicals such as cannabidiol, tetrahydrocannabinol and terpenes. They also interact with the endogenous ligands synthesized bythe human body. The role of nanotechnology in the design of a drug delivery system is discussed in this review. The advantages with theuse of Quantum dots are briefly outlined. Cannabis-based phytochemicals are known for psychotic and non-psychotic effects. We haveunderlined the immense potential of this plant in treating diseases. Cannabidiol (CBD) as one of the main non-psychotic phytochemicals,has established itself as an active pharmaceutical agent in some approved medicines worldwide. Cannabis-based phytochemicals can beused as targeted drug delivery vehicles. Future direction in this field could be a synthesis of derivatives of cannabidiol and its targeteddrug delivery to the cannabinoid receptors. In the oral route, the terpenes give the wholesome experience of consuming Cannabis.

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“…They are fluorescent 0-D (Zero Dimension) nanoparticles used in drug delivery and allow in vivo monitoring. It has disadvantages such as the fact that they are hydrophobic and tend to aggregate, so it has to be coated with a layer of ligands so that they become soluble [ 176 ].…”

Section: Cancer Nanopharmaceuticalsmentioning

confidence: 99%

Cancer Nanopharmaceuticals: Physicochemical Characterization and In Vitro/In Vivo Applications

Zielińska

Szalata

Gorczyński

et al. 2021

Cancers

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Physicochemical, pharmacokinetic, and biopharmaceutical characterization tools play a key role in the assessment of nanopharmaceuticals’ potential imaging analysis and for site-specific delivery of anti-cancers to neoplastic cells/tissues. If diagnostic tools and therapeutic approaches are combined in one single nanoparticle, a new platform called nanotheragnostics is generated. Several analytical technologies allow us to characterize nanopharmaceuticals and nanoparticles and their properties so that they can be properly used in cancer therapy. This paper describes the role of multifunctional nanoparticles in cancer diagnosis and treatment, describing how nanotheragnostics can be useful in modern chemotherapy, and finally, the challenges associated with the commercialization of nanoparticles for cancer therapy.

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Quantum Dots for Pharmaceutical and Biomedical Analysis

Cited by 6 publications

References 132 publications

Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes

Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes

Therapeutic Potential of Cannabis Plant

Cancer Nanopharmaceuticals: Physicochemical Characterization and In Vitro/In Vivo Applications

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