Quantum dots labeling using octa-arginine peptides for imaging of adipose tissue-derived stem cells

Clinical Stem Cell Imaging and In vivo Tracking

“…Depending on the size and composition of these probes, they can be designed to emit different wavelengths of light, ranging from ultraviolet to nearly infrared. Although there are minimal experiences and published reports with their application for the purpose of in vivo stem cell tracking (Lu, Xu et al 2010;Yukawa, Kagami et al 2010), the photostability of QDs, as seen in their resistance to photobleaching and long-lasting fluorescence, suggest them as attractive tools for tracking stem cells in vivo (Lin, Xie et al 2007;Zhang and Wu 2007). However, some concerns about the effects of QDs on stem cell proliferation and differentiation (Hsieh, Wang et al 2006) and safety of this approach have been raised (Ramot, Steiner et al 2010).…”

Peptides as Promising Non-Viral Vectors for Gene Therapy

“…Cargoes of different nature have been delivered. Negatively charged QCs were electrostatically bound to arg 8 and delivered into adipose tissue-derived stem cells for imaging purposes (Yukawa et al, 2010). The anti-cancer drug, taxol was covalently bound to arg 8 via disulfide bonds using a novel linker to increase its water solubility and uptake.…”

Nanobiodevice-based Single Biomolecule Analysis, Single-Cell Analysis, and in vivo Imaging for Cancer Diagnosis, Cancer Theranostics, and iPS Cell-based Regenerative Medicine

“…[1][2][3][4][5][6][7] In this review article, we mainly overview our research activities, including nanobiodevices for single-cell analysis, [20][21][22][23][24][25] single biomolecule analysis, 19,[26][27][28][29]41,46,50,[54][55][56][57][58] biomarker detections, 23,[30][31][32][33]39,[47][48][49] cancer theranostics, and iPS cell in vivo imaging. [20][21][22][23][24][25][34][35][36][37][38]40,[42][43][44][45]…”