Quercetin and Rutin as Potential Sunscreen Agents: Determination of Efficacy by an in Vitro Method

Choquenet, Benjamin; Couteau, Céline; Paparis, Eva; Coiffard, Laurence

doi:10.1021/np7007297

Cited by 142 publications

(108 citation statements)

References 15 publications

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“…Antioxidant phenolics also exhibit sun protection efficacy 23 in particular ferulic, caffeic and rosmarinic acid and quercetin, which are highlighted as new photoprotective agents for topical application products including cosmetics 15,24,25 . To widen the Passion fruit seed application, sun protection efficacy was further monitored.…”

Section: Resultsmentioning

confidence: 99%

Antioxidant Activities and Phenolics of Passiflora edulis Seed Recovered from Juice Production Residue

Lourith

Kanlayavattanakul

2013

J. Oleo Sci.

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Section: Resultsmentioning

confidence: 99%

Antioxidant Activities and Phenolics of Passiflora edulis Seed Recovered from Juice Production Residue

Lourith

Kanlayavattanakul

2013

J. Oleo Sci.

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“…The highest concentrations are found in onion [57]. Quercetin and rutin were tested as potential topical sunscreen factors in human beings and found to provide protection in the UVA and UVB range [65].…”

Section: Phytochemicals Skin Cancer and Rosmentioning

confidence: 99%

Oxidative Stress and Skin Cancer: An Overview

Narendhirakannan

Hannah

2012

Ind J Clin Biochem

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Skin is the largest body organ that serves as an important environmental interface providing a protective envelope that is crucial for homeostasis. On the other hand, it is a major target for toxic insult by a broad spectrum of physical and chemical agents that are capable of altering its structure and function. There are a large number of dietary contaminants and drugs can manifest their toxicity in skin. These environmental toxicants or their metabolites are inherent oxidants and/or directly or indirectly drive the production of a variety of reactive oxidants also known as reactive oxygen species. These are short-lived entities that are continuously generated at low levels during the course of normal aerobic metabolism. These are believed to activate proliferative and cell survival signaling that can alter apoptotic pathways that may be involved in the pathogenesis of a number of skin disorders. The skin possesses an array of antioxidant defense mechanisms that interact with toxicants to obviate their deleterious effect. The ''antioxidant power'' of a food is an expression of its capability both to defend the human organism from the action of the free radicals and to prevent degenerative disorders. Plants like olive trees have their own built-in protection against the oxidative damage of the sun, and these built-in protectors function as cell protectors in our own body. Although many antioxidants have shown substantive efficacy in cell culture systems and in animal models of oxidant injury, unequivocal confirmation of their beneficial effects in human populations has proven elusive.

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“…Literature survey has reported that flavonoids like flavonols 14,15,16] (quercetin, rutin, kaempferol, myricetin, fisetin, vitexin) flavones (apigenin, luteolin) flavanones (naringenin, hesperitn, naringin, and hesperidin), isoflavones 17 originally found at the seashores. Flowers are white in color, 20 fragrant at night and have reddish anthers.…”

Section: Introductionmentioning

confidence: 99%

Chinese Pharmacy Undergraduate Attitudes toward Game-Based Learning in Pharmaceutical Education

Wang¹,

Hu²,

Hu³

et al. 2013

IJPER

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Crinum asiaticum Linn. flowers commonly known as white lily flowers were explored to find flavonoids, so, thin layer chromatography was performed and some of the flavonoids were identified as flavon (Apigenine ), flavonol (Quercetin), flavan-3-ols (Catechin), isoflavones (Daidzein). flavonol (Fisetin, Myricetin and Kaempferol). The reported flavonoids were known to have sunscreen activity and hence SPF factor of the dried flower extract (aqueous) was incorporated in topical formulation and evaluated in vitro with the help of Optometric Model-290 SPF. Extraction of flowers was done in two steps; maceration in MeOH: Water (9:1) followed by maceration in MeOH: Water (1:1) respectively. The two extracts were combined and methanol was then evaporated with the help of rotary evaporator, the resultant aqueous extract was used for Thin Layer Chromatography and then into topical formulation. In vitro determination of SPF was done with the help of method specified by The Comité de Liaison de la Parfumerie in Europe (COLIPA). The SPF was found to be 1.17 and Boots Star rating as 3, indicating that Crinum asiaticum Linn flower extract (aqueous) can be considered as good candidate for Sunscreen or as an additive in any other sunscreen formulation.

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Quercetin and Rutin as Potential Sunscreen Agents: Determination of Efficacy by an in Vitro Method

Cited by 142 publications

References 15 publications

Antioxidant Activities and Phenolics of Passiflora edulis Seed Recovered from Juice Production Residue

Antioxidant Activities and Phenolics of Passiflora edulis Seed Recovered from Juice Production Residue

Oxidative Stress and Skin Cancer: An Overview

Chinese Pharmacy Undergraduate Attitudes toward Game-Based Learning in Pharmaceutical Education

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