Racial/Ethnic Differences in Bone Mineral Density for Osteoporosis

Wu, Qing; Dai, Jingyuan

doi:10.1007/s11914-023-00838-y

Cited by 9 publications

(2 citation statements)

References 124 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most of the gene mutation sites in this study were reported in previous literatures [24][25][26][27][28][29][30][31][32][33][34][35], such as M133L, A159V, etc., which again verified the gene mutation characteristics and formation mechanism of OBI. This study found that there is a certain correlation between HBV S gene mutation and the pathogenesis of OBI, and if the S gene mutation is likely to lead to the omission of OBI.…”

Section: Discussionmentioning

confidence: 81%

Correlation analysis of latent hepatitis B virus infection gene mutation in unpaid blood donors

Yu,

Wang,

Liu

2024

Preprint

View full text Add to dashboard Cite

ObjectiveTo analyze the HBV S region gene mutation in serum samples of occult hepatitis B virus (HBV) infection (OB1), and to further analyze the mechanism of gene mutation and OBI.MethodsBlood samples from unpaid blood donors from January 2022 to December 2023 were collected and analyzed for serology, liver function indicators, viral load and gene mutation.ResultsA total of 90 OBI cases were detected, the detection rate was 0.051%, and the incidence of OBI was correlated with age. The sequence amplification of s region in the blood samples showed the presence of C type and B type genes, both of which occurred in the hydrophilic region.ConclusionThere is no abnormal liver function between OBI and hepatitis B population, and there is no difference in viral load between different serum modes. Mutations in the HBVS region are more likely to cause OBI, which provides a scientific basis for more sensitive HBV detection.

show abstract

Section: Discussionmentioning

confidence: 81%

Correlation analysis of latent hepatitis B virus infection gene mutation in unpaid blood donors

Yu,

Wang,

Liu

2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Each patient was questioned about the presence of possible risk factors for osteoporosis. We recorded age, sex, weight, height and ethnicity for all patients [ 16 ]. We also recorded BMD, T-score, Z-score at each measurement site.…”

Section: Methodsmentioning

confidence: 99%

“The least significant change on bone mineral density scan increased in patients with higher degrees of obesity”

Dorilleau,

Kanagaratnam,

Charlot

et al. 2024

Aging Clin Exp Res

View full text Add to dashboard Cite

Background: The least significant change (LSC) threshold of 0.03 g/cm² is used to interpret bone mineral density (BMD) scans in the general population. Our working hypothesis was that the current LSC threshold would not be applicable in obese populations. Aims: The aim of this study was to calculate the LSC in an obese population. Methods: We performed an interventional study among 120 obesity patients, in whom two measurements of BMD were performed at 3 sites. Pairs of measures were used to calculate the LSC, using the Bland and Altman method. Results: We calculated that the LSC was 0.046 g/cm² at the lumbar spine, 0.069 g/cm² at the femoral neck, and 0.06 g/cm² at the total hip. We also calculated the LSC for each class of obesity and observed an increase in LSC with increasing body mass index (BMI). We calculated a LSC of 0.05 g/cm² in patients with class 2 or class 3 obesity, whereas the LSC in patients with class 1 obesity is similar to the threshold used in the general population. Discussion: In obese population, like BMD, LSC is higher than the threshold value of the general population, and increases with increasing BMI.Conclusion: LSC of 0.05 g/cm² could be used in clinical practice in patients with class 2 or 3 obesity. These findings should help to improve the interpretation of BMD scans in these patients and optimize their management. Trial registration number: Comité de Protection des Personnes Ile-de France VII, France.

show abstract

Letter to the Editor regarding “Associations between ultra-distal forearm bone mineral density and incident fracture in women”

Wang,

Zhao

2024

Osteoporos Int

View full text Add to dashboard Cite

Racial/Ethnic Differences in Bone Mineral Density for Osteoporosis

Cited by 9 publications

References 124 publications

Correlation analysis of latent hepatitis B virus infection gene mutation in unpaid blood donors

Correlation analysis of latent hepatitis B virus infection gene mutation in unpaid blood donors

“The least significant change on bone mineral density scan increased in patients with higher degrees of obesity”

Letter to the Editor regarding “Associations between ultra-distal forearm bone mineral density and incident fracture in women”

Contact Info

Product

Resources

About