This special theme of Big Data & Society explores connections, relationships, and tensions that coalesce around data, power, and racial formation. This collection of articles and commentaries builds upon scholarly observations of data substantiating and transforming racial hierarchies. Contributors consider how racial projects intersect with interlocking systems of oppression across concerns of class, coloniality, dis/ability, gendered difference, and sexuality across contexts and jurisdictions. In doing so, this special issue illuminates how data can both reinforce and challenge colorblind ideologies as well as how data might be mobilized in support of anti-racist movements.