Racial variation in prostate needle biopsy templates directed anterior to the peripheral zone

Feibus, Allison H.; Levy, Justin; McCaslin, Ian; Doucet, Meggie E.; Sholl, Andrew B.; Moparty, Krishnarao; Thomas, Raju; Silberstein, Jonathan L.

doi:10.1016/j.urolonc.2016.03.017

Cited by 2 publications

(3 citation statements)

References 15 publications

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“…Racial characteristics are considered important factors affecting treatment strategies and oncological outcomes of patients with urological tumors. 16 , 17 Disparities were also associated with the quality of medical care, particularly in the US, for economically disadvantaged patients. However, the roles of racial disparities in influencing the outcomes of patients with PUC have been insufficiently characterized, and this subject is thus controversial.…”

Section: Discussionmentioning

confidence: 99%

Sex-related differences in clinicopathological features and survival of patients with primary urethral carcinoma: a population-based study

Wei¹,

Wu²,

Xu³

et al. 2017

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PurposeTo analyze the Surveillance, Epidemiology, and End Results (SEER) database to determine the effects of sex and prognostic factors on the survival of patients with primary urethral carcinoma (PUC).Materials and methodsWe selected 453 patients diagnosed with PUC from 2004 to 2013 from the SEER database. Statistical analysis was used to identify sex-specific differences associated with tumor characteristics and cancer-specific survival (CSS) and overall survival (OS).ResultsCompared with men, there was a higher proportion of black women, more negative lymph-node status, higher American Joint Committee on Cancer (AJCC) stage, more advanced T3 stage, more with adenocarcinoma (Ac), and fewer with squamous cell carcinoma (SCC) or transitional cell carcinoma (TCC). Among women, black race and M1 stage were associated with shorter CSS and OS, respectively. In addition, surgery was associated with longer OS in women. Among men, AJCC III and IV and M1 stages were associated with shorter CSS and OS. In addition, age >75 years associated with shorter OS in men.ConclusionBlack race was associated with shorter OS and CSS of women, and surgery was associated with longer OS of women. Among men, AJCC stage III and IV were associated with shorter OS and CSS. Age >75 years was associated with shorter OS in men only. Women with Ac experienced poor CSS compared with men. Men with TCC experienced worse CSS compared with those with Ac or SCC.

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Section: Discussionmentioning

confidence: 99%

Sex-related differences in clinicopathological features and survival of patients with primary urethral carcinoma: a population-based study

Wei¹,

Wu²,

Xu³

et al. 2017

OTT

View full text Add to dashboard Cite

show abstract

“…45 In a study of 398 men, of whom 70% were African American men, most patients had prostate cancer limited to the peripheral zone or in both the peripheral and anterior to the peripheral zone. 46 For 4% of study patients, prostate cancer was limited to the anterior to the peripheral zone -5% of African Americans vs 2% of those not of African American descent -but this result was not statistically significant. 46 Another study showed a biologically important relationship between tumor location and molecular subtype, but racial differences in molecular subtypes did not persist when tumors were analyzed by location.…”

Section: Biological Etiology Of Disparitymentioning

confidence: 73%

“…46 For 4% of study patients, prostate cancer was limited to the anterior to the peripheral zone -5% of African Americans vs 2% of those not of African American descent -but this result was not statistically significant. 46 Another study showed a biologically important relationship between tumor location and molecular subtype, but racial differences in molecular subtypes did not persist when tumors were analyzed by location. 47 The study investigated triple-negative disease and AR signaling.…”

Section: Biological Etiology Of Disparitymentioning

confidence: 73%