Radial Optic Neurotomy for Central Retinal Vein Occlusion: Long-Term Retinal Perfusion Outcome

Callizo, Josep; Kroll, P.; Mennel, Stefan; Schmidt, Jan Peter; Meyer, Carsten H.

doi:10.1159/000217730

Cited by 15 publications

(9 citation statements)

References 42 publications

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“…After 1 year, retinal perfusion improved in 63.1% of operated eyes and 14.3% of controls. The visual improvement in the RON group was significantly better than in the control group [18]. Although this study did not compare hemodynamics but only if a central retinal vein occlusion changed from ischemic to nonischemic or not, these findings are in contrast to our data.…”

Section: Discussioncontrasting

confidence: 89%

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Radial Optic Neurotomy in Central Retinal Vein Occlusion Does Not Influence Ocular Hemodynamics

et al. 2010

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Purpose: Radial optic neurotomy (RON) is used for the treatment of central retinal vein occlusion. Its effects on visual acuity differ substantially between patients. Our study aims to evaluate if RON has an impact on ocular microcirculation and if analysis of ocular microcirculation might serve as a predictor for surgical success. Procedures: A complete ophthalmologic examination including color Doppler imaging of the retrobulbar vessels was performed before and 2–4 months after RON in 12 patients. Results: Mean visual acuity was 0.09 ± 0.03 prior to and 0.24 ± 0.12 after RON. Visual acuity improved in 7 (+3.5 ± 0.9 lines), was stable in 3 (±0 lines) and worsened in 2 cases (–6 and –2 lines). Doppler parameters were not affected by RON, and no correlations between visual acuity and perfusion parameters were found. Conclusions: Our data indicate that RON does not influence ocular microcirculation. None of the assessed hemodynamic parameters appears to be a predictor for surgical success.

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Section: Discussioncontrasting

confidence: 89%

“…Callizo et al [18] analyzed the long-term changes in retinal perfusion and functional improvements in 63 consecutive patients. Twenty-eight patients underwent RON and 35 were followed as a control.…”

Section: Discussionmentioning

confidence: 99%

Radial Optic Neurotomy in Central Retinal Vein Occlusion Does Not Influence Ocular Hemodynamics

et al. 2010

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“…These results indicated that intravitreal injections may be superior to previous surgical treatment modalities in RVO (Callizo et al. 2009).…”

Section: Discussionmentioning

confidence: 78%

Functional and anatomical results after a single intravitreal Ozurdex injection in retinal vein occlusion: a 6‐month follow‐up – The SOLO study

Bezatis

Spital

Höhn

et al. 2013

Acta Ophthalmologica

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ABSTRACT.Purpose: To evaluate the efficacy of intravitreal dexamethasone implants in eyes with cystoid macular oedema (CME) secondary to branch retinal vein occlusion (BRVO) or central retinal vein occlusion (CRVO) in the clinical everyday practice, examine the effects of early retreatment and compare the results with the GENEVA study. Methods: The charts of 102 patients (102 eyes) with CME secondary to BRVO (n = 54) or CRVO (n = 48) treated with Ozurdex at 8 centres were retrospectively reviewed. The patients were examined monthly over a 24-week period. Slit-lamp biomicroscopy, measurement of best-corrected visual acuity (BCVA) and measurement of the central retinal thickness (CRT) with spectral-domain optical coherence tomography (SD-OCT) were performed at baseline and at every follow-up examination. The mean CRT at baseline was 740 ± 351 lm and it decreased to 419 ± 315 lm after 4 weeks, 352 ± 261 lm after 8 weeks, 455 ± 251 lm after 12 weeks, 497 ± 280 lm after 16 weeks, 468 ± 301 lm after 20 weeks and 395 ± 234 lm after 24 weeks. The BCVA improvement was statistically significantly better (p < 0.05) compared with baseline in both groups at every follow-up visit. The mean CRT maintained significantly better when compared with baseline in both groups at all follow-up visits. Early reinjection was indicated in BRVO in 40.7% after 17.5 ± 4.2 weeks and in CRVO in 50% after 17.68 ± 4.2. Six eyes (11%) with BRVO received a sectorial laser photocoagulation at a mean interval of 22 ± 5.0 weeks. Seven eyes (15%) with CRVO received a panretinal laser photocoagulation after a mean interval of 18 ± 7.0 weeks. The BCVA improvement and the mean CRT reduction were statistically significant (p < 0.05) compared with baseline in both groups at every follow-up visit. Conclusions: Dexamethasone intravitreal implant resulted in a significant improvement of the BCVA and reduction of CME in patients with BRVO or CRVO. Early retreatment after 16 weeks instead of 24 weeks, like in the GENEVA study, was indicated in 50% to stabilize the improved functional and anatomical results.

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“…Macular ischemia affects visual outcome, irrespective of the duration of ME [17]. The visual prognosis of patients with macular edema who are treated with intravitreal bevacizumab is influenced by the presence of retinal ischemia [18, 19]. In our study, the nongainer group showed an increased frequency of macular ischemia.…”

Section: Discussionmentioning

confidence: 54%

Consecutive Macular Edema and Visual Outcome in Branch Retinal Vein Occlusion

Baek

Kwon

Park

et al. 2014

Journal of Ophthalmology

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Purposes. The study introduced the concept of “consecutive macular edema” and evaluated the validity of visual outcome in macular edema (ME) secondary to branch retinal vein occlusion (BRVO). Methods. Patients were categorized into the gainer group and the nongainer group according to the final visual acuity. We analyzed clinical characteristics involving total and consecutive duration of ME between the two groups. Results. Among the total 71 eyes of 71 patients, intravitreal bevacizumab injection (26 patients), triamcinolone (21), and natural course (33) were enrolled. The consecutive duration of ME was shorter in the gainer group than in the nongainer group (3.33 ± 1.50 and 5.24 ± 2.39 months; P = 0.000). After exclusion of macular ischemia, consecutive duration of ME in gainer group was also significantly shorter than in nongainer group (3.62 ± 1.60 and 6.11 ± 4.20 months; P = 0.010). Conclusions. The duration of ME in the nongainer group was longer than in the gainer group. In particular, the consecutive duration was an important factor in determining the final visual outcome. Clinical Trial Registration. Approval by Hallym University Sacred Heart Hospital Institutional Review Board/Ethics Committee was obtained for this retrospective study.

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Radial Optic Neurotomy for Central Retinal Vein Occlusion: Long-Term Retinal Perfusion Outcome

Cited by 15 publications

References 42 publications

Radial Optic Neurotomy in Central Retinal Vein Occlusion Does Not Influence Ocular Hemodynamics

Radial Optic Neurotomy in Central Retinal Vein Occlusion Does Not Influence Ocular Hemodynamics

Functional and anatomical results after a single intravitreal Ozurdex injection in retinal vein occlusion: a 6‐month follow‐up – The SOLO study

Consecutive Macular Edema and Visual Outcome in Branch Retinal Vein Occlusion

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