Radiation-activated nanoparticles: Which combination to optimize radiosensitization?

Penninckx, Sébastien; Martinive, Philippe; Mirjolet, Céline

doi:10.1016/j.canrad.2023.07.002

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Radiotherapy and Hadrontherapy1

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2024

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“…Since the first report of J.F. Hainfield et al in 2004 [138], the association of metallic nanoparticles with X-rays (radiotherapy) or particle beams (hadrontherapy) seems a promising approach to improve treatments in cancer therapy [139][140][141]. Indeed, metallic NPs with a high atomic number Z (gold and platinum) combined with ionizing radiation can enhance the effect of radiotherapy or hadrontherapy.…”

Section: Radiotherapy and Hadrontherapymentioning

confidence: 99%

Synthesis of Metallic Nanostructures Using Ionizing Radiation and Their Applications

Remita,

Lampre

2024

Materials

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This paper reviews the radiation-induced synthesis of metallic nanostructures and their applications. Radiolysis is a powerful method for synthesizing metallic nanoparticles in solution and heterogeneous media, and it is a clean alternative to other existing physical, chemical, and physicochemical methods. By varying parameters such as the absorbed dose, dose rate, concentrations of metallic precursors, and nature of stabilizing agents, it is possible to control the size, shape, and morphology (alloy, core-shell, etc.) of the nanostructures and, consequently, their properties. Therefore, the as-synthesized nanoparticles have many potential applications in biology, medicine, (photo)catalysis, or energy conversion.

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Section: Radiotherapy and Hadrontherapymentioning

confidence: 99%