Radiation Dose and Risk Estimates of CT-Guided Percutaneous Liver Ablations and Factors Associated with Dose Reduction

McCarthy, Colin J.; Kilcoyne, Aoife; Li, Xinhua; Cahalane, Alexis M.; Liu, Bob; Arellano, Ronald S.; Uppot, Raul N.; Gee, Michael S.

doi:10.1007/s00270-018-2066-1

Cited by 5 publications

(8 citation statements)

References 48 publications

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“…Last, regarding the technique used, it had no impact on the dose delivered after analysis weighted with age, sex, location and number of helical acquisitions. For MWA and RFA, our results are consistent with a previous study in percutaneous liver ablations (11). Our recovered doses for these two techniques remain quite close to those found in other studies (11,19,20).…”

Section: Discussionsupporting

confidence: 92%

“…For MWA and RFA, our results are consistent with a previous study in percutaneous liver ablations (11). Our recovered doses for these two techniques remain quite close to those found in other studies (11,19,20). Regarding cryoablation, it seems to deliver higher doses than the other techniques.…”

Section: Discussionsupporting

confidence: 91%

“…Only few monocentric studies have evaluated factors that may impact the dose delivered during abdominal percutaneous destructions. McCathy et al showed in 245 patients an increase of the dose delivered during percutaneous hepatic ablation under CT guidance by RFA, MWA and electroporation, correlated with weight, intravenous injection of contrast product, hydrodissection during the procedure and multiple lesions (11). Two other monocentric single-organ and single-technique studies evaluated the technical parameters correlated to the dose in cryotherapy percutaneous destruction in 97 patients with kidney lesions (12) and in 18 patients with liver lesions (13) but patient characteristics (age, gender, weight, etc.)…”

Section: Discussionmentioning

confidence: 99%

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A national dose analysis of guided tumor destruction: influence of sex, age, localization and destruction technique used

Rojo¹,

Hamard²,

Serrand³

et al. 2022

Quant Imaging Med Surg

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Background: Percutaneous destructions of tumor lesions by ablation (microwave, radiofrequency or cryoablation) under computed tomography (CT) guidance allow high efficiency with minimally-invasive techniques, and acute needle placement and follow-up during procedure. This study investigated the impact of patient and technique parameters on the dose delivered during these procedures under CT guidance.Methods: Data were extracted from a previous nationwide retrospective study. Patients who underwent percutaneous destruction of bone lesions, abdominal and lung tumors were included. Univariate and multivariate linear regression of the dose length product (DLP) log were performed, according to patient's gender, age, lesion location, destruction technique, adjusted to the participating center.Results: A total of 822 patients (556 men), of mean age 62±14 years, were included: 150 patients had bone lesions, 463 abdominal and 209 thoracic tumors. The mean DLP was 991.6±979.0 mGy•cm for patients with bone lesions, 2,130.7±2,051.8 mGy.cm for abdominal tumors and 825.2±545.4 mGy•cm for lung tumors. In multivariate analysis, the age was significantly associated with higher DLP for bone (P=0.0082) but not for abdominal and thoracic lesions; the DLP was significantly higher in men for abdominal tumors (P<0.0001) while sex had no impact on the dose for bone and thoracic lesions. The dose depended on the lesion location only for bone (P<0.0001) percutaneous destructions. The technique was not correlated to DLP for all lesions.Conclusions: Patient and tumor characteristics such as sex, age and lesion location impacted on the dose delivered during percutaneous destructions of bone, abdominal and thoracic lesions, but not the destruction technique used. Further studies are needed to propose sharper reference dose levels.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A national dose analysis of guided tumor destruction: influence of sex, age, localization and destruction technique used

Rojo¹,

Hamard²,

Serrand³

et al. 2022

Quant Imaging Med Surg

View full text Add to dashboard Cite

show abstract

“…The AUC was equal to 0.7896 with optimal ROC point coordinate of (0.3261, Fig. 2 Boxplots showing the four predicting variables distribution for the two dependent variable categories: P KA >300 Gy cm 2…”

Section: Binary Logistic Regression Modelmentioning

confidence: 99%

“…Multivariable logistic regression (MLR) analysis has been widely used as a method to identify prognostic factors affecting medical treatments outcome. 2 The aim of this study was to analyze radiation dose-related metrics available from the angiographic system and from the radiology information system (RIS) and to use MLR to estimate the occurrence of high radiation dose procedures.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Factors Affecting Air Kerma Area Product Obtained during Uterine Artery Embolization Procedures Using Logistic Regression

Soliman

Almutairi

AlHarbi

et al. 2021

Indian J Radiol Imaging

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Purpose Uterine artery embolization (UAE) is a common interventional radiology procedure used in medicine; the procedure is safe but there is always a concern regarding radiation dose received by the patient. The aim of this study was to use multivariable logistic regression analysis (MLRA) to study a certain number of independent prognostic variables believed to provide an estimate of the likelihood of obtaining a high kerma area product (P KA) at the end of the procedure. Method Radiation dose indices registered by the angiographic system structured dose report, the total fluoroscopy time (FT), the patient’ body mass index (BMI), the number of images taken during the procedures (IMGS), and the performing physician experience (EXPER) were used to drive a logistic regression model (LRM). Results The LRM found was: Logit (P KA) = −6.1525 + 0.0416 (FT) + 0.1028 (IMGS) + 0.1675 (BMI) – 0.1012 (EXPER). The prediction accuracy of the LRM was assessed using receiver operating characteristic (ROC) curve; by calculating the area under the curve (AUC), we found AUC = 0.7896, with optimal ROC point of 0.3261, 0.8036. Conclusion The suggested LRM seems to indicate that patients with higher BMI, have taken longer FT, acquired higher IMGS and the procedure done by a less experienced performing physician is more susceptible to receive a higher P KA at the end. The proposed LRM is useful in predicting the occurrence of higher radiation exposure interventions and can be used in patients’ radiation dose optimization strategies during UAE procedures.

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Analysis of patients receiving ≥ 100 mSv during a computed tomography intervention

2020

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Radiation Dose and Risk Estimates of CT-Guided Percutaneous Liver Ablations and Factors Associated with Dose Reduction

Cited by 5 publications

References 48 publications

A national dose analysis of guided tumor destruction: influence of sex, age, localization and destruction technique used

A national dose analysis of guided tumor destruction: influence of sex, age, localization and destruction technique used

Analysis of Factors Affecting Air Kerma Area Product Obtained during Uterine Artery Embolization Procedures Using Logistic Regression

Analysis of patients receiving ≥ 100 mSv during a computed tomography intervention

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