Radiation doses from low-dose CT scans in SPECT/CT and PET/CT examinations: A survey in Germany

Rinscheid, Andreas; Janzen, Tilman; Alikhani, Babak; Beer, Ambros; Braune, Anja; Eberhardt, Nina; Fechner, Diana; Förster, Stefan; Freesmeyer, Martin; Furth, Christian; Grunert, Michael; Hellwig, Dirk; Costa, Pedro Fragoso; Kühnel, Christian; Lange, Catharina; Linke, Rainer; Razlaw, Natalia; Sack, Tobias; Schmidt, Daniel; Schütze, Christina; Starke, Alexander; Tondera, Liane; Wengenmair, H.; Zöphel, Klaus; Burchert, Wolfgang; Lapa, Constantin

doi:10.1055/a-1759-3900

Cited by 3 publications

(2 citation statements)

References 15 publications

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“…Furthermore, the literature review highlighted that variation in NDRL value for the administered activities related to the stress and rest one-day protocol range from 407 MBq and 740 MBq to 555 MBq and 1184 MBq for 99m Tc-Tetrofosmin /Sestamibi, respectively [ 8 , 11 , 12 ]. Regarding CT components, a few articles reflect the change of variation in NDRL related to the CT dose, for instance, the CTDI vol value ranges from 2.2 mGy to 36 mGy and the DLP value ranges from 36 mGy.cm to 380 mGy.cm [ 13 , 14 , 15 , 16 , 17 ].…”

Section: Introductionmentioning

confidence: 99%

Radiation Dose Assessment for Myocardial Perfusion Imaging: A Single Institution Survey

et al. 2023

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Objective: This study aims to establish a local diagnostic reference level (LDRL) for single-photon emission tomography/computed tomography (SPECT/CT) and positron emission tomography/CT (PET/CT) with respect to myocardial perfusion imaging (MPI). Materials and Methods: The acquisition protocol and dosimetry data on the MPI procedures of five SPECT/CT scans and one PET/CT scan were collected. Data on technitum-99m sestamibi (99mTc-sestamibi), 99mTc-tetrofosmin, thallium-201 (201Tl), and rubidium-82 (82RB) were all collected from one centre via questionnaire booklets. Descriptive data analysis was used to analyse all variables, and the 50th percentile was used to analyse each radiation dose quantity. Results: The reported 50th percentile dose for a one-day stress/rest protocol using 99mTc-sestamibi (445/1147 MBq) and 99mTc-tetrofosmin (445/1147 MBq) and for a two-day stress/rest protocol using 99mTc-sestamibi (1165/1184 MBq) and 99mTc-tetrofosmin (1221/1184 MBq) are in good agreement with reported national diagnostic reference levels (NDRLs). However, the dose from the study data on a one-day stress/rest protocol using 99mTc-sestamibi was more than the 50th percentile dose from the Brazilian data (370/1110 MBq) on a similar protocol, and the dose from the study data on a two-day stress/rest protocol using 99mTc-tetrofosmin was more than the 50th percentile dose (1084/1110 MBq) from the United States data on MPI scans. Regarding the computed tomography (CT) portion of the SPECT/CT framework, the 50th percentile doses were lower than all the identified doses in the data considered in the literature reviewed. However, regarding the CT component of the PET/CT MPI scans, the 82RB dose was more than the recorded doses in the CT data in the published literature. Conclusion: This study determined the LDRL of five SPECT/CT protocols and one PET/CT MPI protocol. The results suggest that there may be opportunities to optimise the patient radiation burden from administered activities in patients undergoing SPECT examinations and the CT components associated with 82RB PET/CT scans without compromising diagnostic image quality.

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Section: Introductionmentioning

confidence: 99%

Radiation Dose Assessment for Myocardial Perfusion Imaging: A Single Institution Survey

et al. 2023

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“…There are several NDRLs in the literature for a wide range of SPECT/CT scans over the globe [12][13][14]. A search of the literature demonstrates a variation in reporting NDRL for SPECT/CT exam, for example, stress/rest myocardial perfusion scan between the United States (425 MBq/1221 MBq) and France (300 MBq/800 MBq) [9,11].…”

Section: Introductionmentioning

confidence: 99%

The establishment of national diagnostic reference levels for adult SPECT-CT in Saudi Arabia

Al-Qahtani,

Alidasroos,

Alkhybari

et al. 2023

J. Radiol. Prot.

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This study aims to introduce national diagnostic reference levels )NDRLs) for adult hybrid SPECT/CT in nuclear medicine (NM) departments in the Kingdom of Saudi Arabia. The Adminis-tered Activity (AA) of radiopharmaceuticals, volume-weighted computed tomography dose index (CTDIvol) and dose length product (DLP) for ten hybrid SPECT/CT examinations were collected and analyzed for one year. The median of AA, CTDIvol and DLP for each dose quantity was derived and the suggested national DRLs were determined based on the 75th percentile for all identified SPECT/CT examinations. A comparison of the defined adult NDRLs in Saudi Arabia with the pub-lished data of other countries was performed. Although there are no significant variations of the proposed NDRL of AA between countries, the proposed NDRLs of the integrated CT metrics ex-ceed the published data in most procedures. NM departments are urged to consider optimization for both image quality and radiation protection.

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Evaluation of patients’ radiation doses and establishment of institutional diagnostic reference levels in nuclear medicine in Oman

Ebrahim,

Aljabri,

Alhaji

et al. 2024

Radiation Protection Dosimetry

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This study aimed to develop diagnostic reference levels (DRLs) in Single Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) and Positron Emission Tomography/Computed Tomography (PET/CT) imaging for the most frequent SPECT/CT and PET/CT examinations performed at our institution. A total of 1134 adult patients, who have undergone SPECT/CT and PET/CT scanning over a period of 4 years (2018–2021), were included. The scans consisted of 401 PET/CT and 733 SPECT/CT scans. The CT dosimetry data [CT-dose-index (CTDIvol), dose-length-product (DLP)] and administered activities were collected. The DRLs were calculated for CTDIvol, DLP and administrated activity. The estimated DRLs are given as [median CTDIvol (mGy):median DLP (mGy.cm):median administrated activity (MBq)]: whole body PET/CT: 1.88:175:259; brain PET/CT: 12.9:300:239; cardiac PET/CT: 1.34:32:368; bone SPECT/CT: 2.68:116:763; MPI SPECT/CT (stress-rest): 1.49:52:751-721; parathyroid SPECT/CT: 3.1:126:779; thyroid uptake SPECT: 3.52:147:195; thyroid post-ablation SPECT/CT: 3.85:160:NA. The derived DRLs have allowed careful monitoring of doses delivered to patients and could act as a trigger to investigate doses that systematically exceeds the derived DRLs.

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Radiation doses from low-dose CT scans in SPECT/CT and PET/CT examinations: A survey in Germany

Cited by 3 publications

References 15 publications

Radiation Dose Assessment for Myocardial Perfusion Imaging: A Single Institution Survey

Radiation Dose Assessment for Myocardial Perfusion Imaging: A Single Institution Survey

The establishment of national diagnostic reference levels for adult SPECT-CT in Saudi Arabia

Evaluation of patients’ radiation doses and establishment of institutional diagnostic reference levels in nuclear medicine in Oman

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