Radiation late effects in children treated for orbital rhabdomyosarcoma

Perioperative Intensity-Modulated Brachytherapy for Refractory Orbital Rhabdomyosarcomas in Children

“…Despite all advances, there is, however, still a significant overall number of therapy-related side effects impairing the quality of life in this young patient group [6,19,22,[36][37][38][39]49]. IMRT appears to offer a dosimetric advantage compared to conformal techniques [32].…”

Adverse events of local treatment in long-term head and neck rhabdomyosarcoma survivors after external beam radiotherapy or AMORE treatment

“…Since RMS primarily occurs in young children, adverse events (AEs) may be more severe. Published reports on AEs of local treatment in HNRMS survivors were predominantly retrospective or based on questionnaires [6,8,9,[11][12][13][14][15][16]. For adequate follow-up and treatment of the often complex AEs, a systematic prospective assessment is essential.…”

Ethical Analysis as a Tool for Addressing Treatment Controversies: Radiotherapy Timing in Children With Orbital Rhabdomyosarcoma as a Case Example

“…Fiorillo et al [26] noted that lacrimal duct stenosis (leading to xerophthalmia) is amenable to easy and successful management. Likewise, cataracts are among the most prevalent radiation-induced side effects and are easily amenable to surgical removal.…”