Radiation therapy for primary squamous cell carcinoma of the vagina: Stanford University experience

Primary Invasive Vaginal Carcinoma Treated with Radiotherapy: Analysis of Prognostic Factors

“…In our group, age had an important influence on survival: [1-3, 5, 7-10, 12, 14, 17, 22], but, particularly in the early stages, they are not as favorable as reported by Gallup et al for patients below the age of 60, the percentage of a 5-year NED survival rate is 63.2%, for those over 60 years of age (100 and 75% in stages I and II, respectively) [22], Spirtos et al (94 and 80%) [23], and Leung and Sexton (90% stage it reaches only 25%. In the group presented by Vavra et al…”

Effect of radiotherapeutic technique on local control in primary vaginal carcinoma

“…Statistically significant lower local control rates noted in patients treated with teletherapy alone have been reported previously by Peters and co-workers (7) and Spirtos and coUeagues (5). However, these two studies could demonstrate a difference in local control only when 75 Gy total mid-tumor dose was used as the dividing point.…”

“…Although radiotherapy is the predominant method of treating carcinoma of the vagina, local control rates vary widely among different reports (3)(4)(5)(6). One 4oo G. L. Eddy et al dominant factor in these differences is the radio° therapeutic technique employed.…”

Radiotherapy of vaginal carcinoma

“…In Anlehnung an die Strategien bei Vulva-oder Zervixkarzinomen kann oftmals der Organ-und Funktionserhalt erzielt werden.Aufgrund der kleinen Patientenzahlen können derzeit weder das Risiko von Spätkomplikationen noch der Profit für Langzeitüberleben und Lokalkontrolle sicher beurteilt werden [7,25].…”