Radical lymph node resection of the retroperitoneal area for left-sided colon cancer

Abstract

Radical lymph node resection of the retroperitoneal area is associated with the same rate of hospital morbidity, late urogenital morbidity, and total survival as is conventional surgery. It seems that there is a trend for improvement of survival particularly in stage III patients.

Short-term outcomes after complete mesocolic excision compared with ‘conventional’ colonic cancer surgery

“…Based on the literature, there may be selection and publication bias. The 30-day mortality rate found in this study is similar to findings reported previously by others 5,14,19,20 . This study also reported 90-day mortality, as the elderly and patients with co-morbidities have an increased risk of dying between 30 and 90 days after surgery 21 -23 .…”

Complete mesocolic resection and extended lymphadenectomy for colon cancer: a systematic review

“…Seven were documented as prospective cohort studies. Five series had controls, of which only one was randomized [3,4,[23][24][25]. The total analysable included population was 5246 CME/ EL cases.…”

“…The mean age of the patients included was 62.2 years (five studies did not include patient age or gender) and 56.5% were men [4,10,[23][24][25]. Approximately 50% of neoplasms were right-sided lesions ( Table 2).…”

“…Two studies included emergency procedures, of which 142 (9.1%) were performed [1,30]. The mean operative time for CME/EL resections was 151 (range, 136-156) min vs 137 (range, 36-145) min for standard procedures [1,[3][4][5][6][10][11][12][23][24][25][26][27][28][29][30][31][32][33][34][35]. The mean length of stay was 10.3 (3-12) days for CME/EL compared with 8.2 (3-12) days for standard resections [10,11,[26][27][28][29]35].…”

Biology-Based Surgery: The Extent of Lymphadenectomy in Cancer of the Colon

“…Although radical resection resulted in a significantly higher LNC, no difference in the number of positive nodes or survival was found. Similarly, a prospective single-center trial by Tentes et al [36] compared periaortic LN resection for left-sided CC with conventional surgery in 124 patients. Again, despite a significantly higher LNC after radical resection, no significant difference in the number of involved nodes or survival was noted although improved survival in stage III patients was found after radical resection ( p = 0.04).…”