Radiofrequency ablation for benign thyroid nodule treatment: New solution in our center

Bellynda, Monica; Kamil, Kamil; Yarso, Kristanto Yuli

doi:10.1016/j.ijscr.2022.107418

Cited by 4 publications

(3 citation statements)

References 25 publications

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“…Recent nonsurgical data indicate that 4-6.5% of all thyroid nodules are malignant. Upon detecting a thyroid nodule, the initial diagnostic test should involve assessing thyroid status via a TSH measurement [31,32]. Subsequently, all patients with a suspected nodule or nodules should undergo a thyroid USG to conduct a sonographic risk assessment [33,34].…”

Section: Thyroid Nodules 21 Diagnosismentioning

confidence: 99%

Thyroid Nodules and Biopsy

Serdar Deniz

2024

Hypothyroidism - Causes, Screening and Therapeutic Approaches [Working Title]

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The present chapter provides an in-depth review of the prevalence, diagnostic challenges, and management strategies for thyroid nodules, emphasizing the integration of various diagnostic modalities to enhance precision and guide therapeutic decisions. Thyroid nodules are frequently encountered in clinical settings, with a significant proportion detected incidentally. While most are benign, the potential for malignancy necessitates careful evaluation, primarily through ultrasound-guided fine-needle aspiration (FNA). However, FNA has limitations, including unsatisfactory and indeterminate results, which may lead to unnecessary interventions. The chapter discusses the evolution of diagnostic techniques, including the role of ultrasonography, molecular diagnostics, and core needle biopsy, alongside traditional FNA. It highlights recent clinical experiences and studies that address diagnostic ambiguities, aiming to optimize patient outcomes by reducing unnecessary surgeries and improving diagnostic accuracy. The impact of external factors, such as the COVID-19 pandemic on thyroid nodule diagnostics, is explored. Through a comprehensive analysis, the chapter seeks to provide clinicians with updated strategies and insights into managing thyroid nodules effectively in diverse clinical contexts.

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Section: Thyroid Nodules 21 Diagnosismentioning

confidence: 99%

Thyroid Nodules and Biopsy

Serdar Deniz

2024

Hypothyroidism - Causes, Screening and Therapeutic Approaches [Working Title]

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“…Under the guidance of ultrasound, high-frequency alternating current is generated through radiofrequency electrodes, which cause polar molecules and electrons in the tissue to oscillate at high speed, thereby generating heat 6. When the temperature approaches 50 °C, the protein solidifies, leading to necrosis of the tumor cells and thus elimination of the tumor 7 . This surgical method has the advantages of small trauma, quick recovery, high safety and good efficacy, so it is often used in the clinical treatment of tumors and nodules 6 , 8 .…”

Section: Introductionmentioning

confidence: 99%

Risk factors of recurrent thyroid nodules after radiofrequency ablation

Xia,

Fu,

Qian

et al. 2023

Afr H. Sci.

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Objective: To investigate the risk factors of thyroid nodule recurrence after radiofrequency ablation (RFA). Methods: The medical record information of 120 patients with thyroid nodules admitted to our hospital from June 2019 to April 2022 was retrospectively analysed. All participants received RFA treatment. According to the results of the postoperative thyroid ultrasoundexamination (USG), the patients were divided into the recurrence group (R, N=16) and the non-recurrence group (NR,N=104). Binary logistic regression analysis was performed to identify the independent risk factors of thyroid nodule recurrenceafter RFA. The receiver operating characteristic (ROC) curve was used to analyse the value of the forecast of each independentfactor and combined model for thyroid nodule recurrence after RFA. Results: During the follow-up period, 16 patients recurred, and the recurrence rate was 13.33%. Univariate regression analysisshowed that whether the nodules are solitary (WNS), nodule diameter (ND), the degree of risk of nodular location (DRN),recurrent laryngeal nerve (RLN) injury were associated with thyroid nodule recurrence after RFA (P<0.05). Binary logisticregression analysis showed that WNS, ND, DRN and RLN injury were independent risk factors for the recurrence of thyroidnodules after RFA (P<0.05). ROC analysis of independent factors and combined model showed that solitary nodules, nodulediameter and nodule location risk degree had diagnostic value, while RLN injury had no predictive value. The combined modelis more predictive than the independent factors. Conclusions: The risk factors of recurrent thyroid nodules after radiofrequency ablation are related to WNS, ND, DRN and so on, which should be paid attention to and preventive measures should be taken. Keywords: Thyroid nodules; radiofrequency ablation; recurrence; risk factors.

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“…In the relationship between breast cancer and thyroid cancer, a significant association with benign thyroid disease was also found in a previous study [ 13 ]. Thyroid nodules are clinically important because thyroid cancer is diagnosed in approximately 4.0–6.5% of thyroid nodules [ 14 ]. Larger thyroid nodules and higher thyroid-stimulating hormone levels are associated with a higher risk of thyroid cancer [ 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

The Role of Blood Microbiome in the Development of Thyroid Cancer in Breast Cancer Survivors

An,

Kwon,

Kim

2023

Cancers

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Patients diagnosed with breast cancer are likely to be diagnosed with thyroid cancer as a second primary cancer. Similarly, patients with thyroid cancer are likely to develop breast cancer. In this study, we found an association between these two types of cancers in the microbiomes of patients with breast cancer. Blood samples were collected from 96 patients with breast cancer, their bacterial extracellular vesicles were isolated, and their microbiomes were analyzed. After microbiome analysis, researchers performed thyroid function tests, estrogen levels, and thyroid ultrasound results of these patients, and the relationships among these parameters were analyzed. Based on the thyroid ultrasonography results, differences in the microbiome were confirmed in the normal, cyst, nodule, and thyroid lobectomy groups. We investigated the microbiome differences between normal thyroid and thyroid cancer. In particular, the abundance of the genus Bacillus is related to estrogen levels, which could affect thyroid abnormalities and increase thyroid-stimulating hormone levels. This study explains the causes of thyroid cancer in patients with breast cancer using microbiomes and serological tests for thyroid hormones and estrogen. These can be used as basic data for preventing thyroid cancer in patients with breast cancer.

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Radiofrequency ablation for benign thyroid nodule treatment: New solution in our center

Cited by 4 publications

References 25 publications

Thyroid Nodules and Biopsy

Thyroid Nodules and Biopsy

Risk factors of recurrent thyroid nodules after radiofrequency ablation

The Role of Blood Microbiome in the Development of Thyroid Cancer in Breast Cancer Survivors

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