Radiofrequency ablation technique in the treatment of liver tumours: review and future issues

Abstract

Thermal ablation is increasingly being used for treatment of liver tumours. Among the techniques of thermal ablation, radiofrequency ablation (RF) is undoubtedly being used most frequently because of its advantages, such as morbidity and mortality rates, effective tumour ablation, as well as being less time-consuming. This paper presents the state of the art of RF ablation technique. This includes the theoretical development, experimental study and clinical application of the radiofrequency ablation technique. First, it introduces the principle of this technique. Second, it shows the development of this technique and valuable achievements. These achievements include the device, strategy of operation and extension to other diseases. Third, it concludes future issues to be addressed in order to further advance this technique.

A new approach to feedback control of radiofrequency ablation systems for large coagulation zones

“…Radiofrequency ablation (RFA) uses alternating electric current with high frequency (about 500 kHz) to generate heat in the tumour tissue and to ablate the tumour tissue based on the thermal effect. Specifically, heat is generated in biological tissue through a circuit that consists of the electrode, tumour tissue, normal tissue, grounding pad and RF power generator, [1,2] and this circuit is called RFA system. This method is used for the treatment of liver tumours as well as tumours in bone, lung and kidney.…”

Hepatocellular Carcinoma Treatment: Percutaneous Ablation Treatments

“…İşlem sonucunda tümöral dokunun tamamının ve tümörü çevreleyen 1 cm'lik normal karaciğer dokusunun yok edilmesi amaçlanır. 4 E El le ek kt tr ro ot t T Ti ip pl le er ri i ( (R Re es si im m 1 1 a a--c c) ) 1 1) ) " "C Co oo ol le ed d" " t ti ip p: : Elektrotların prototipidir. Dondurulmuş serum fizyolojik (SF) ile işlem esnasında sürekli soğutulmaktadır.…”

Cooled tip radiofrequency ablation of benign thyroid nodules: preliminary experience with two different devices

“…In particular, RFA is a minimally invasive treatment that had been used for benign and malignant tumors in liver, kidney and lung, resulting in long-term tissue necrosis (9)(10)(11).…”