Radiofrequency ablation therapy in patients with breast cancers two centimeters or less in size

Oura, Shoji; Tamaki, Takeshi; Hirai, Ikuko; Yoshimasu, Tatsuya; Ohta, Fuminori; Nakamura, Rie; Okamura, Yoshitaka

doi:10.2325/jbcs.14.48

Cited by 109 publications

(83 citation statements)

References 16 publications

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“…A combination of follow-up and immediate or delayed surgical excision was performed in two studies (49 patients). [32, 33] Follow-up with imaging alone or imaging and core biopsies was performed in nine studies (220 patients) [21,23,24,30,31,60,66,68,73]. Reasons for performing a treat and resect study or a follow-up study were often not reported.…”

Section: 4±09)mentioning

confidence: 99%

“…When looking at complete ablation rates of RFA studies that followed patients up with core needle biopsy (CNB) and imaging but without surgical excision, complete ablation was achieved in 98.0±4.0% (100/102) [30,32,66,68], in follow-up studies using cryo-ablation 100% (6/6) of patients had complete ablation [21] Treat and resect studies also undertook patient follow-up. RFA studies used MRI (n=6), US (n=4), mammography (n=2) or CT (n=1) for follow-up up to one month after surgical excision, laser ablation studies used MRI (n=2), US (n=1), CT (n=1) and mammography (n=1) for follow-up up to two weeks after surgical excision and every three months thereafter, cryo-ablation studies used MRI (n=3) or US (n=1) for follow-up up to one month after surgical excision, HIFU studies used MRI (n=5) for follow-up up to three weeks J U S T A C C E P T E D after surgical excision, and microwave ablation studies used MRI (n=1) or US (n=1) up to three weeks prior to surgical excision.…”

Section: J U S T a C C E P T E Dmentioning

confidence: 99%

See 1 more Smart Citation

Minimally invasive ablative techniques in the treatment of breast cancer: a systematic review and meta-analysis

Peek

Ahmed

Napoli

et al. 2016

International Journal of Hyperthermia

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Purpose: Breast conserving surgery is effective for breast cancer treatment but is associated with morbidity in particular high re-excision rates. We performed a systematic review to assess the current evidence for clinical outcomes with minimally invasive ablative techniques in the non-surgical treatment of breast cancer.Methods: A systematic search of the literature was performed using PubMed and Medline library databases to identify all studies published between 1994 and May 2016. Studies were considered eligible for inclusion if they evaluated the role of ablative techniques in the treatment of breast cancer and included ten patients or more. Studies that failed to fulfil the inclusion criteria were excluded. Results:We identified 63 studies including 1608 patients whose breast tumours were treated with radiofrequency (RFA), high intensity focused ultrasound (HIFU), cryo-, laser or microwave ablation. Fifty studies reported on the number of patients with complete ablation as found on histopathology and the highest rate of complete ablation was achieved with RFA (87.1%, 491/564) and microwave ablation (83.2%, 89/107). Short-term complications were most often reported with microwave ablation (14.6%, 21/144). Recurrence was reported in 24 patients (4.2%, 24/570) and most often with laser ablation (10.7%, 11/103). The shortest treatment times were observed with RFA (15.6±5.6 minutes) and the longest with HIFU (101.5±46.6 minutes).

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Section: 4±09)mentioning

confidence: 99%

Section: J U S T a C C E P T E Dmentioning

confidence: 99%

Minimally invasive ablative techniques in the treatment of breast cancer: a systematic review and meta-analysis

Peek

Ahmed

Napoli

et al. 2016

International Journal of Hyperthermia

View full text Add to dashboard Cite

show abstract

“…Oura et al [20] in their series of 52 patients with breast cancers of mean size 1.3 cm. Multifocality, multicentricity and tumour size were thoroughly investigated prior to RFA and patients with multiple malignant areas or large tumours were excluded.…”

Section: Radiofrequency Ablationmentioning

confidence: 99%

“…A FEM model was used in this work because it can provide users with quick, accurate solutions to multiple systems of differential equations and therefore, they are well suited to solve heat transfer problems like ablation [27]. Numerous MWA antenna designs specifically targeted for MWA cardiac and hepatic applications have been reported [20][21][22][23][24], but they have not been used to treat breast cancer. These designs have been focused largely on thin, coaxial-based interstitial antennas [28], which are minimally invasive and capable of delivering a large amount of electromagnetic power.…”

Section: Advanced Computer Modeling In Breast Cancer Hyperthermia Trementioning

confidence: 99%

High Temperature Hyperthermia in Breast Cancer Treatment

Rubio¹,

Salas²

2013

Hyperthermia

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“…The major technical problem with electromagnetic hyperthermia is the difficulty of heating the target tumor at the desired temperature without damaging the surrounding tissues. MNPs of various types may address this issue through intracellular hyperthermia or ablation; i.e., by driving submicron magnetic particles inside the tumor and then making them generate heat under an alternating magnetic field [12].…”

Section: Introductionmentioning

confidence: 99%

Improved Thermal Ablation Efficacy Using Magnetic Nanoparticles: A Study in Tumor Phantoms

García-Jimeno¹,

Ortega-Palacios²,

Rubio³

et al. 2012

PIER

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Abstract-Magnetic heating used for inducing hyperthermia and thermal ablation is particularly promising in the treatment of cancer provided that the therapeutic temperature is kept constant during the treatment time throughout the targeted tissue and the healthy surrounding tissues are maintained at a safe temperature. The present study shows the temperature increment produced by different concentrations of magnetic nanoparticles (ferrofluid and magnetoliposomes) inside a phantom, after irradiating tissuemimicking materials (phantoms)with a minimally invasive coaxial antenna working at a frequency of 2.45 GHz. This frequency was chosen because maximum dielectric loss of water molecules begins at 2.4 GHz and because this is an ISM (industrial, scientific and medical) frequency. Temperature sensors were placed inside and outside the tumor phantom to assess the focusing effect of heat produced by nanoparticles. Results have shown that the temperature increments depend on the nanoparticles concentration. In this way, a temperature increment of more than 56 • C was obtained with a ferrofluid concentration of 13.2 mg/mL, whereas the increment in the reference phantom was only of ≈ 21 • C. Concerning the magnetoliposomes, the temperature achieved was similar to that obtained with the ferrofluid but at a lesser concentration of nanoparticles. These results

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Radiofrequency ablation therapy in patients with breast cancers two centimeters or less in size

Abstract: RFA can be safely used for breast cancer and provides good local control and excellent cosmesis to patients with small breast cancers.

Cited by 109 publications

References 16 publications

Minimally invasive ablative techniques in the treatment of breast cancer: a systematic review and meta-analysis

Minimally invasive ablative techniques in the treatment of breast cancer: a systematic review and meta-analysis

High Temperature Hyperthermia in Breast Cancer Treatment

Improved Thermal Ablation Efficacy Using Magnetic Nanoparticles: A Study in Tumor Phantoms

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