Radiofrequency ablation versus surgical resection for single nodule hepatocellular carcinoma: Long‐term outcomes

Abstract

Although the groups were not truly comparable, this retrospective study suggests that RFA may offer similar long-term results to surgical resection for single nodule HCC when combined with multimodal treatments.

Radiofrequency Ablation for Hepatocellular Carcinoma: Updated Review in 2010

“…5). Similar findings were also noted in other reports [12,13,14,15,16,17,18]. Based on these, resection is recommended for cases with 3 or fewer tumors 3 cm or smaller in which resection is readily applicable with regard to the liver function and localization, and only a small amount of liver tissue is sacrificed, but RFA is recommended for tumors located in a deep region, when the liver function capacity is graded as Child-Pugh B, or the tumor extends over the bilateral lobes.…”

Radiofrequency Ablation Versus Resection for Liver Tumours: An Evidence-Based Approach to Retrospective Comparative Studies

“…18,[21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40] All studies were retrospective except for three which were prospective, 27,30,34 including two randomized trials. 30,34 Some studies reported specific data for solitary 18,22,24,26,28,32,34,36,39,40 or small tumours. 18,22,26,[30][31][32][34][35][36]40 A study based on a theoretical mathematical analysis using the Markov modelling to simulate a randomized trial of RFA and HR for HCC less than 5 cm was also retrieved and discussed, but its numeric data were not included.…”

Systematic review and meta-analysis of survival and disease recurrence after radiofrequency ablation for hepatocellular carcinoma

“…Eight articles included patients outside the Milan criteria in their comparison between RFA (797 patients) and resection (712 patients) 24,44,48,49,52,58,60,61 . Because of larger numbers and sizes of tumours, four of the studies combined RFA with TACE 48,52,60,61 .…”