Radiographic and Clinical Features in Morquio's Syndrome

Myelopathy in a dwarf: A case of Morquio′s syndrome without odontoid hypoplasia

“…On imaging, the characteristic spinal deformity in Morquio's syndrome is platyspondylia (flat vertebra). [2] The other X-ray findings of Morquio's syndrome are, hypoplastic or absent dens with C1/C2 instability, anterior tongue of thoracic vertebrae, hookshaped lumbar vertebral bodies, and wide disc spaces. [3] MRI findings are spinal cord compression at C1/C2.…”

“…[3] MRI findings are spinal cord compression at C1/C2. [2] Patients with this syndrome present to neurosurgeon with chronic compressive high cervical myelopathy with involvement of corticospinal tract, posterior columns and spinothalamic tract in descending order. The pathogenesis of myelopathy is atlanto-axial subluxation, stenosis of foramen magnum or atlas and compression by soft tissue mass both anteriorly as well as posteriorly.…”