Radiologist-Patient Communication: Current Practices and Barriers to Communication in Breast Imaging

Aminololama-Shakeri, Shadi; Soo, Mary Scott; Grimm, Lars J.; Watts, Meredith; Poplack, Steven P.; Rapelyea, Jocelyn A.; Saphier, Nicole; Stack, Rand J.; Destounis, Stamatia

doi:10.1016/j.jacr.2018.10.016

Cited by 22 publications

(3 citation statements)

References 20 publications

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“…We used the Selective Evolution of Ligands by Exponential enrichment (SELEX) method ( Burke and Gold, 1997 ; Horii et al, 2010 ) to prepare selective targeting nucleotides that showed high binding affinity to the oAβ conformation. After preparing Gd-DOTA as previously described ( Kielar et al, 2010 ; Huynh et al, 2017 ), we synthesized Gd-DOTA-ob5 as described previously ( So et al, 2006 ; Dudeffant et al, 2017 ; Aminololama-Shakeri et al, 2019 ; Li and Meade, 2019 ; Kim et al, 2023 ) and evaluated its ability to detect oAβ deposits in the brain using MRI.…”

Section: Methodsmentioning

confidence: 99%

Oligomeric amyloid-β targeted contrast agent for MRI evaluation of Alzheimer’s disease mouse models

Park,

Tian,

Kim

et al. 2024

Front. Pharmacol.

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BackgroundOligomeric amyloid beta (oAβ) is a toxic factor that acts in the early stage of Alzheimer’s disease (AD) and may initiate the pathologic cascade. Therefore, detecting oAβ has a crucial role in the early diagnosis, monitoring, and treatment of AD.PurposeThe purpose of this study was to evaluate MRI signal changes in different mouse models and the time-dependent signal changes using our novel gadolinium (Gd)-dodecane tetraacetic acid (DOTA)- ob5 aptamer contrast agent.MethodsWe developed an MRI contrast agent by conjugating Gd-DOTA-DNA aptamer called ob5 to evaluate its ability to detect oAβ deposits in the brain using MRI. A total of 10 control mice, 9 3xTg AD mice, and 11 APP/PS/Tau AD mice were included in this study, with the age of each model being 16 or 36 weeks. A T1-weighted image was acquired at the time points before (0 min) and after injection of the contrast agent at 5, 10, 15, 20, and 25 min. The analyses were performed to compare MRI signal differences among the three groups and the time-dependent signal differences in different mouse models.ResultsBoth 3xTg AD and APP/PS/Tau AD mouse models had higher signal enhancement than control mice at all scan-time points after injection of our contrast media, especially in bilateral hippocampal areas. In particular, all Tg AD mouse models aged 16 weeks showed a higher contrast enhancement than those aged 36 weeks. For 3xTg AD and APP/PS/Tau AD groups, the signal enhancement was significantly different among the five time points (0 min, 5 min, 10 min, 15 min, 20 min, and 25 min) in multiple ROI areas, typically in the bilateral hippocampus, left thalamus, and left amygdala.ConclusionThe findings of this study suggest that the expression of the contrast agent in different AD models demonstrates its translational flexibility across different species. The signal enhancement peaked around 15–20 min after injection of the contrast agent. Therefore, our novel contrast agent targeting oAβ has the potential ability to diagnose early AD and monitor the progression of AD.

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Section: Methodsmentioning

confidence: 99%

Oligomeric amyloid-β targeted contrast agent for MRI evaluation of Alzheimer’s disease mouse models

Park,

Tian,

Kim

et al. 2024

Front. Pharmacol.

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“…Nonetheless, communication skill training in radiology appears to be sporadically provided. In a 2019 survey by the Society of Breast Imaging, two-thirds of breast imagers, arguably the most patient centered of the radiology subspecialties, would seek additional communication training [2], whereas a 2018 survey of radiology residents, 6 years after the inclusion of communication as a core competency, revealed that 84% of residents still had no communication training [3].…”

Section: Communication Skill Trainingmentioning

confidence: 99%

Emerging From Behind the Workstation

Dodelzon

Katzen

2022

Journal of the American College of Radiology

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“…In this context, breast radiologists (BR), key figures in BC prevention, diagnosis, and follow-up programs, routinely navigate complex communicative scenarios. Their role entails a crucial responsibility to establish a proper relationship with the patient and caregiver, especially when revealing the disease’s initial diagnosis or progression [ 5 , 6 ]. The BR’s ability to articulate results, discuss potential diagnoses, and guide patients through the most appropriate diagnostic and therapeutic pathway is essential to ensure comprehensive patient-centered care.…”

Section: Introductionmentioning

confidence: 99%

Radiologists’ Communicative Role in Breast Cancer Patient Management: Beyond Diagnosis

Mariano,

Nicosia,

Sorce

et al. 2024

Healthcare

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In the landscape of cancer treatment, particularly in the realm of breast cancer management, effective communication emerges as a pivotal factor influencing patient outcomes. This article delves into the nuanced intricacies of communication skills, specifically spotlighting the strategies embraced by breast radiologists. By examining the ramifications of communication on patient experience, interdisciplinary collaboration, and legal ramifications, this study underscores the paramount importance of empathetic and comprehensive communication approaches. A special emphasis is placed on the utilization of the SPIKES protocol, a structured method for conveying sensitive health information, and the deployment of strategies for navigating challenging conversations. Furthermore, the work encompasses the significance of communication with caregivers, the integration of artificial intelligence, and the acknowledgement of patients’ psychological needs. By adopting empathetic communication methodologies and fostering multidisciplinary collaboration, healthcare practitioners have the potential to enhance patient satisfaction, promote treatment adherence, and augment the overall outcomes within breast cancer diagnosis. This paper advocates for the implementation of guidelines pertaining to psychological support and the allocation of sufficient resources to ensure the provision of holistic and patient-centered cancer care. The article stresses the need for a holistic approach that addresses patients’ emotional and psychological well-being alongside medical treatment. Through thoughtful and empathetic communication practices, healthcare providers can profoundly impact patient experiences and breast cancer journeys in a positive manner.

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Radiologist-Patient Communication: Current Practices and Barriers to Communication in Breast Imaging

Cited by 22 publications

References 20 publications

Oligomeric amyloid-β targeted contrast agent for MRI evaluation of Alzheimer’s disease mouse models

Oligomeric amyloid-β targeted contrast agent for MRI evaluation of Alzheimer’s disease mouse models

Emerging From Behind the Workstation

Radiologists’ Communicative Role in Breast Cancer Patient Management: Beyond Diagnosis

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