“…However, for mammographic density, this has not been established. Some studies report no heterogeneity in the association between mammographic density and breast cancer tumor characteristics;12–22 while others indicate differences by hormone receptor status,3,23–28 invasiveness,22,29 phenotype,30,31 tumor size,22,26,28,32,33 and stage 34. Most studies have limited the assessment of mammographic density qualitatively as defined by the BI-RADS classification, or quantitatively as percent dense area (PDA); the other mammographic density parameters, dense area (DA) and non-dense area (NDA) have seldom been taken into account.…”