Radiomics analysis based on CT’s greater omental caking for predicting pathological grading of pseudomyxoma peritonei

Zhou, Nan; Dou, Ruixue; Zhai, Xichao; Fang, Jingyang; Wang, Jiajun; Ma, Ruiqing; Xu, Jingxu; Cui, Bin; Liang, Lianchun

doi:10.1038/s41598-022-08267-0

Cited by 2 publications

(3 citation statements)

References 38 publications

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“…However, the inconstant association of scalloping with long-term outcomes from one series to another suggest that this sign is not solely reflective of PMP behaviour. Scalloping could therefore be considered as a secondary sign of advanced disease, but not sufficient on its own to tailor treatment strategy while awaiting the development of radiomics [ 47 ], which will hopefully overcome these limitations.…”

Section: Discussionmentioning

confidence: 99%

Scalloping of the Liver and Spleen on Preoperative CT-Scan of Pseudomyxoma Peritonei Patients: Impact on Prediction of Resectability, Grade, Morbidity and Survival

Képénékian

Kefleyesus

Keskin

et al. 2022

Cancers

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Pseudomyxoma peritonei (PMP) is ideally treated by cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC), leading to significant morbidity. Beyond the histologic grade, the prognosis lies in the completeness of cytoreduction (CC-score of 0/1 vs. 2/3) and the severe complication rate. The mucinous nature of the peritoneal implants sometimes induces liver and/or spleen scalloping on imaging. The predictive value of scalloping was assessed regarding resectability, grade, survival and severe morbidity. This monocentric, retrospective analysis compared CC-0/1 with CC-2/3 groups regarding liver and spleen scalloping parameters, assessed on pre-operative computed tomography (CT) scan, reviewed for the study. In addition, prognostic factors of severe complications and recurrence-free and overall survivals were explored in the CC-0/1 population. Overall, 129 patients were included (109 CC-0/1, 20 CC-2/3), with 58 (45%) exhibiting scalloping. All patients with splenic scalloping also had a liver one. Scalloping was more frequent (75% vs. 39%), with greater median maximal depth (21 vs. 11 mm) and higher PCI (32 vs. 14) in the CC-2/3 population, but was not predictive of either grade or survival. In CC-0/1 patients, survivals and postoperative complications were not affected by scalloping parameters. Scalloping appeared as a marker of advanced PMP, but was not predictive of grade, severe complications, or long-term outcomes.

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Section: Discussionmentioning

confidence: 99%

Scalloping of the Liver and Spleen on Preoperative CT-Scan of Pseudomyxoma Peritonei Patients: Impact on Prediction of Resectability, Grade, Morbidity and Survival

Képénékian

Kefleyesus

Keskin

et al. 2022

Cancers

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“…Few studies have focused on the management of patients with peritoneal carcinosis using radiomics-based clinical-practice-decision-support tools [156][157][158].…”

Section: What Radiologists Need To Know About Radiomics and Pcimentioning

confidence: 99%

“…Liu et al used radiomic models for the preoperative prediction of occult peritoneal metastasis (PM) in advanced gastric cancer (AGC) using CT images. They were able to show that the radiomic analysis of venous CT based on the primary tumor provided valuable information with which to predict occult PM in AGCs [158].…”

Section: What Radiologists Need To Know About Radiomics and Pcimentioning

confidence: 99%

Peritoneal Carcinosis: What the Radiologist Needs to Know

Reginelli,

Giacobbe,

Del Canto

et al. 2023

Diagnostics

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Peritoneal carcinosis is a condition characterized by the spread of cancer cells to the peritoneum, which is the thin membrane that lines the abdominal cavity. It is a serious condition that can result from many different types of cancer, including ovarian, colon, stomach, pancreatic, and appendix cancer. The diagnosis and quantification of lesions in peritoneal carcinosis are critical in the management of patients with the condition, and imaging plays a central role in this process. Radiologists play a vital role in the multidisciplinary management of patients with peritoneal carcinosis. They need to have a thorough understanding of the pathophysiology of the condition, the underlying neoplasms, and the typical imaging findings. In addition, they need to be aware of the differential diagnoses and the advantages and disadvantages of the various imaging methods available. Imaging plays a central role in the diagnosis and quantification of lesions, and radiologists play a critical role in this process. Ultrasound, computed tomography, magnetic resonance, and PET/CT scans are used to diagnose peritoneal carcinosis. Each imaging procedure has advantages and disadvantages, and particular imaging techniques are recommended based on patient conditions. Our aim is to provide knowledge to radiologists regarding appropriate techniques, imaging findings, differential diagnoses, and treatment options. With the advent of AI in oncology, the future of precision medicine appears promising, and the interconnection between structured reporting and AI is likely to improve diagnostic accuracy and treatment outcomes for patients with peritoneal carcinosis.

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Radiomics analysis based on CT’s greater omental caking for predicting pathological grading of pseudomyxoma peritonei

Cited by 2 publications

References 38 publications

Scalloping of the Liver and Spleen on Preoperative CT-Scan of Pseudomyxoma Peritonei Patients: Impact on Prediction of Resectability, Grade, Morbidity and Survival

Scalloping of the Liver and Spleen on Preoperative CT-Scan of Pseudomyxoma Peritonei Patients: Impact on Prediction of Resectability, Grade, Morbidity and Survival

Peritoneal Carcinosis: What the Radiologist Needs to Know

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