A series of measurements were conducted to study the indoor radon pollution in air-conditioned high-rise office buildings. Continuous monitoring of indoor radon levels in nine air-conditioned premises located in six office buildings in Hong Kong was conducted from August 1996 to February 1998. Each of the tests lasted for at least 48 hours. The measurement covered both day time monitoring while the air-conditioning was on and night time monitoring while the air-conditioning was off. The indoor radon level followed inversely the operation pattern of the mechanical ventilation systems in the buildings. During office hours when the mechanical ventilation was on, the indoor radon level decayed and after the mechanical ventilation was off during non-office hours, the radon level increased. The average indoor radon level during office hours on the nine premises varied from 87 Bq/m3 to 296 Bq/m3, and the indoor averaged radon levels over both day time and night time periods without mechanical ventilation were about 25 percent higher. The air infiltration rate and the radon emission characteristics from the building materials were estimated from the radon build-up curves which were observed after the mechanical ventilation was off. The radon decay curve observed after the mechanical ventilation system was turned on was used to calculate the total fresh air intake rate. Average radon emanation rates of the building materials in the six buildings varied from 0.0019 to 0.0033 Bq/m2s. It has been found that building infiltration rate accounted for about 10-30 percent of the total building ventilation rate in the buildings depending on building tightness.