Randomized controlled trial of preoperative oral carbohydrate treatment in major abdominal surgery

Mathur, Sachin; Plank, Lindsay D.; McCall, John L.; Shapkov, P; McIlroy, Kerry; Gillanders, LK; Merrie, Arend E. H.; Torrie, Jocelyn; Pugh, F; Koea, J.; Bissett, Ian P.; Parry, Bryan R.

doi:10.1002/bjs.7026

Cited by 122 publications

(141 citation statements)

References 29 publications

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“…This result appropriate with the research by Mathur et al at New Zealand, on patient undergoing elective major abdominal surgery, that compared sample groups who got oral glucose solution preoperatively on night and morning 2 hours before induction of anesthesia compared with placebo groups that result significant decrease in cortisol level on the sample groups who got oral glucose solution than placebo groups on the first day after surgery [7]. This result also matched to the theoretical concept that administration of oral glucose solution preoperatively can trigger the insulin secretion, thus change the patient's metabolic status from fasted state to fed state [8].…”

Section: Discussionsupporting

confidence: 75%

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Metabolic Stress Response Attenuate by Oral Glucose Preoperatively in Patient Underwent Major Surgery with General Anesthesia

Widnyana¹,

Senapathi²,

Aryabiantara³

et al. 2017

Int J Anesth Pain Med

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Background: Fasting, anesthesia and surgery lead to metabolic stress response. Increase of cortisol level lead to insulin resistance and hyperglicemic state has significant effect to the wound healing and increase morbidity and mortality to the patient undergoing surgery. The aim of this research is to prove that preoperative oral glucose loading can decrease metabolic stress response and also the difference effect on preoperative oral glucose that given twice and once time to decrease metabolic stress response in patient undergoing major oncology surgery.

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Section: Discussionsupporting

confidence: 75%

“…The level of significance was p<0.05. The entire data analysis of this study will be done with SPSS version 20 for Windows [7].…”

Section: Methodsmentioning

confidence: 99%

Metabolic Stress Response Attenuate by Oral Glucose Preoperatively in Patient Underwent Major Surgery with General Anesthesia

Widnyana¹,

Senapathi²,

Aryabiantara³

et al. 2017

Int J Anesth Pain Med

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“…27,[154][155][156] In contrast, the results of a larger randomized controlled trial showed no significant benefit. 157 A recent meta-analysis, however, suggests that preoperative administration of oral carbohydrates accelerates recovery after major abdominal surgery. 158 The current ERAS guidelines, therefore, recommend the routine use of preoperative carbohydrate drinks.…”

Section: Assessment Of Catabolism Before Surgerymentioning

confidence: 99%

Perioperative catabolism

Schricker

Lattermann

2015

Can J Anesth/J Can Anesth

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“…24 Ben zer olum suz so nu ca sa hip Mat hur ve ark.nın ça lış ma sın da da kon trol gru bu kul la nıl -ma mış, "ra hat sız lık his si" gi bi sub jek tif bir his değer len di ril miş ve la pa ros ko pik ve ya açık cer ra hi ler, epi du ral anes te zi uy gu la nan ve ya uy gu lan ma yan has ta lar bi r a ra da de ğer len di ril miş tir. 25 Bu lan tı ve kus ma pos to pe ra tif dö nem de has talar açı sın dan ağ rı dan bi le da ha ra hat sız edi ci ola bilen, ta bur cu luk sü re si ni uza ta rak mor bi di te ve ma li ye ti ar tı ran bir yan et ki dir. Ha u sel ve ark.…”

Section: Tar Tiş Maunclassified

The Effect of Preoperative Oral Carbohydrate Loading on Stress Response in Patients Undergoing Major or Minor Surgery

Özdemir¹,

Etı²,

Dinçer³

et al. 2011

Turkiye Klinikleri J Med Sci

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Ö ÖZ ZE ET T A Am ma aç ç: : Bu ça lış ma nın ama cı, ma jör ve mi nör cer ra hi ge çi ren has ta lar da pre o pe ra tif oral karbonhidrat yük le me si nin aç lık, su suz luk, ağız ku ru lu ğu, hal siz lik his si, bu lan tı-kus ma, stres cevap, ba ğır sak ha re ket le ri ve ta bur cu luk sü re si üze ri ne et ki si ni araş tır mak tır. G Ge e r re eç ç v ve e Y Yö ön n t te em m l le er r: : Doksan has ta ma jör ve mi nör cer ra hi ola rak iki gru ba (n= 45), her grup da ken di için de ça lış ma (Ç), pla se bo (P) ve kon trol (K) ol mak üze re üç alt gru ba ay rıl dı. Ça lış ma gru bu na ope ras yon ön ce sin deki ge ce 800 ml ve ope ras yon dan iki sa at ön ce 400 ml oral karbonhidrat içe ce ği, pla se bo gru bu na ise ay nı mik tar lar da su içi ril di. Kon trol gru bu na her han gi bir sı vı içi ril me di. Pre o pe ra tif su suz luk, aç -lık, ağız ku ru lu ğu ve pos to pe ra tif bu lan tı-kus ma ve hal siz lik his si de ğer len di ril di. Pe ro pe ra tif ve pos to pe ra tif altıncı ve 24. sa at ler de plaz ma in sü lin, kor ti zol ve kan glu koz de ğer le ri öl çül dü. Posto pe ra tif ba ğır sak ha re ket le ri nin baş lan gıç za ma nı ve has ta ne den çı kış sü re le ri kay de dil di. B Bu ul l g gu u --l la ar r: : İki fark lı cer ra hi de de Ç ve P gru bun da aç lık, su suz luk ve ağız ku ru lu ğu his si olan has ta sa yı sı K gru bun dan dü şük bu lun du (p< 0.05). Er ken pos to pe ra tif dö nem de bu lan tı-kus ma sı ol ma yan hasta sa yı sı Ç gru bun da di ğer grup lar dan be lir gin yük sek ti (p< 0.01). Kan glu koz de ğer le ri Ç gru bunda 24. sa at te pre operatif de ğer le ri ne dö ner ken, K ve P grup la rın da 24. sa at te de be lir gin yük sek bu lun du (p< 0.01). İnsü lin de ğer le ri Ç gru bun da pos to pe ra tif altıncı sa at te, K ve P grup la rın da ise 24. sa at te be lir gin yük sel di (p< 0.01). Mi nör cer ra hi de ba ğır sak ha re ket le ri baş la ma za ma nı Ç grubun da di ğer le rin den be lir gin kı sa bu lun du (p< 0.01). S So o n nu uç ç: : Pre o pe ra tif karbonhidrat tan zen gin sı -vı ve ya su içi ril me si nin aç lık, su suz luk ve ağız ku ru lu ğu his si ni azalt tı ğı, karbonhidrat tan zen gin sı vı içi ril me si nin bu lan tı-kus ma yı ve in sü lin di ren ci ni azalt tı ğı, mi nör cer ra hi son ra sı ba ğır sak ha reket le ri nin er ken baş la ma sı nı sağ la dı ğı so nu cu na va rıl mış tır.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Pre o pe ra tif ba kım; per hiz; stres, fiz yo lo jik A AB BS S T TR RA AC CT T O Ob b j je ec c t ti i v ve e: : The aim was to in ves ti ga te the ef fects of pre o pe ra ti ve oral car bohy dra te admi nis tra ti on on hun ger, thirst or dryness of the mo uth, na u se a-vo mi ting, the on set ti me of bo wel mo ve ments, disc har ge ti me and the stress res pon se of the pa ti ents un der go ing ma jor or mi nor surgery. M Ma a t te e r ri i a al l a an nd d M Me et t h ho od ds s: : Ninety pa ti ents we re di vi ded in to two gro ups as ma jor and mi nor surgery. Each gro up was di vi ded in to three sub gro ups as study, pla ce...

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Randomized controlled trial of preoperative oral carbohydrate treatment in major abdominal surgery

Abstract: ACTRN012605000456651 (http://www.anzctr.org.au).

Cited by 122 publications

References 29 publications

Metabolic Stress Response Attenuate by Oral Glucose Preoperatively in Patient Underwent Major Surgery with General Anesthesia

Metabolic Stress Response Attenuate by Oral Glucose Preoperatively in Patient Underwent Major Surgery with General Anesthesia

Perioperative catabolism

The Effect of Preoperative Oral Carbohydrate Loading on Stress Response in Patients Undergoing Major or Minor Surgery

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